OLD family nuclease function across diverse anti-phage defense systems
K Akritidou, BH Thurtle-Schmidt - Frontiers in Microbiology, 2023 - frontiersin.org
Bacteriophages constitute a ubiquitous threat to bacteria, and bacteria have evolved
numerous anti-phage defense systems to protect themselves. These systems include well …
numerous anti-phage defense systems to protect themselves. These systems include well …
A virally-encoded tRNA neutralizes the PARIS antiviral defence system
N Burman, S Belukhina, F Depardieu, RA Wilkinson… - Nature, 2024 - nature.com
Viruses compete with each other for limited cellular resources, and some deliver defense
mechanisms that protect the host from competing genetic parasites1. PARIS is a defense …
mechanisms that protect the host from competing genetic parasites1. PARIS is a defense …
Functionally comparable but evolutionarily distinct nucleotide-targeting effectors help identify conserved paradigms across diverse immune systems
While nucleic acid-targeting effectors are known to be central to biological conflicts and anti-
selfish element immunity, recent findings have revealed immune effectors that target their …
selfish element immunity, recent findings have revealed immune effectors that target their …
[HTML][HTML] Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection
N Burman, S Belukhina, F Depardieu, RA Wilkinson… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Viruses compete with each other for limited cellular resources, and some viruses deliver
defense mechanisms that protect the host from competing genetic parasites. PARIS is a …
defense mechanisms that protect the host from competing genetic parasites. PARIS is a …