Drug delivery systems composed of osteogenic substances and biological materials are of
great significance in enhancing bone regeneration, and appropriate biological carriers are …

Articular cartilage defects always progress to degenerative osteoarthritis (OA) and
negatively affect the quality of life for millions of people globally. Biofabrication technologies …

Methacrylation was performed on fibrinogen to design a new biomedical hydrogel for 3D cell
culture or as a biodegradable delivery matrix for in vivo implantation. The methacrylation of …

As hypoxia plays a significant role in the formation and maintenance of cartilage tissue,
aiming to develop native hypoxia-mimicking tissue engineering scaffolds is an efficient …

The goal of the current study is to develop an extracellular matrix bioink that could mimic the
biochemical components present in natural blood vessels. Here, we have used an …

Osteochondral defect caused by trauma or osteoarthritis exhibits a major challenge in
clinical treatment with limited symptomatic effects at present. The regeneration and …

The clinical challenge in the successful management of oral cancer malignancy remains in
the inaccuracy of detecting regional invasion potential and inefficient treatment of recurrent …

Three-dimensional printing technology with the rapid development of printing materials are
widely recognized as a promising way to fabricate bioartificial bone tissues. In consideration …

Cells can 'sense'physical cues in the surrounding microenvironment and 'react'by changing
their function. Previous studies have focused on regulating the physical properties of the …

Bone tissue remodeling is a highly regulated process balancing bone formation and
resorption through complex cellular crosstalk between resident bone and microenvironment …