Importance Stroke is the fifth leading cause of death and a leading cause of disability in the
United States, affecting nearly 800 000 individuals annually. Observations Sudden …

Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations in a single document for clinicians caring for adult …

Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients
with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide …

Background Mechanical thrombectomy (MT) has become the cornerstone of acute ischemic
stroke management in patients with large vessel occlusion (LVO). Objective To assist …

Endovascular thrombectomy (EVT) is well established as a highly effective treatment for
acute ischemic stroke (AIS) due to proximal, large vessel occlusions (PLVOs). With iterative …

Abstract EDITOR'S NOTE The article “Update on Treatment of Acute Ischemic Stroke” by Dr
Rabinstein was first published in the February 2017 Cerebrovascular Disease issue of …

CNS small vessel disease (CSVD) causes 25% of strokes and contributes to 45% of
dementia cases. Prevalence increases with age, affecting about 5% of people aged 50 …

The treatment of acute ischemic stroke continues to advance. The mainstay of treatment
remains intravenous thrombolysis with alteplase. Recent studies demonstrated that later …

Importance Intravenous thrombolysis is increasingly used in patients with minor stroke, but
its benefit in patients with minor nondisabling stroke is unknown. Objective To investigate …

Acute ischaemic stroke is a major public health priority and will become increasingly
relevant to neurologists of the future. The cornerstone of effective stroke care continues to be …