Off-label use of intravenous thrombolysis for acute ischemic stroke: a critical appraisal of randomized and real-world evidence

G Tsivgoulis, O Kargiotis… - Therapeutic …, 2021 - journals.sagepub.com
Intravenous thrombolysis (IVT) represents the only systemic reperfusion therapy able to
reverse neurological deficit in patients with acute ischemic stroke (AIS). Despite its …

Intravenous thrombolysis versus antiplatelet therapy in minor stroke patients with large vessel occlusion

C Duan, Y Xiong, H Gu, S Wang… - CNS Neuroscience …, 2023 - Wiley Online Library
Aim Our study aimed to explore the effectiveness and safety of intravenous t‐PA compared
with dual antiplatelet therapy (DAPT) and aspirin alone for minor stroke with National …

StrokeClassifier: ischemic stroke etiology classification by ensemble consensus modeling using electronic health records

HJ Lee, LH Schwamm, LH Sansing, H Kamel… - NPJ Digital …, 2024 - nature.com
Determining acute ischemic stroke (AIS) etiology is fundamental to secondary stroke
prevention efforts but can be diagnostically challenging. We trained and validated an …

Predictors of outcomes in patients with mild ischemic stroke symptoms: MaRISS

JG Romano, H Gardener, I Campo-Bustillo, Y Khan… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Although most strokes present with mild symptoms, these have
been poorly represented in clinical trials. The objective of this study is to describe …

Redefined measure of early neurological improvement shows treatment benefit of alteplase over placebo

S Agarwal, E Scher, A Lord, J Frontera, K Ishida… - Stroke, 2020 - Am Heart Assoc
Background and Purpose—The first of the 2 NINDS (National Institute of Neurological
Disorders and Stroke) Study trials did not show a significant increase in early neurological …

Pterostilbene alleviates abdominal aortic aneurysm via inhibiting macrophage pyroptosis by activating the miR-146a-5p/TRAF6 axis

H Cai, L Huang, M Wang, R Liu, J Qiu, Y Qin, X Yao… - Food & Function, 2024 - pubs.rsc.org
Pterostilbene (PTE), a natural stilbene found in blueberries and several varieties of grapes,
has several pharmacological activities, including anti-inflammatory and antioxidative …

Updated trends, disparities, and clinical impact of neuroimaging utilization in ischemic stroke in the Medicare population: 2012 to 2019

JJ Wang, CE Pelzl, A Boltyenkov, JM Katz… - Journal of the American …, 2022 - Elsevier
Objective The purpose of this study was to update trends, investigate sociodemographic
disparities, and evaluate the impact on mortality of stroke neuroimaging across the United …

[HTML][HTML] Using tenecteplase for acute ischemic stroke: what is the hold up?

T Zitek, R Ataya, I Brea - Western Journal of Emergency Medicine, 2020 - ncbi.nlm.nih.gov
Alteplase is the only Food and Drug Administration-approved intravenous (IV) thrombolytic
medication for acute ischemic stroke. However, multiple recent studies comparing …

Chinese Stroke Association guidelines for clinical management of ischaemic cerebrovascular diseases: executive summary and 2023 update

L Liu, Z Li, H Zhou, W Duan, X Huo, W Xu… - Stroke and vascular …, 2023 - svn.bmj.com
Background China is one of the countries with the highest burden of stroke. Implementing
multidimensional management guidelines will help clinicians practise evidence-based care …

Perfusion imaging and clinical outcome in acute minor stroke with large vessel occlusion

P Seners, C Arquizan, L Fontaine, W Ben Hassen… - Stroke, 2022 - Am Heart Assoc
Background: Whether bridging therapy (intravenous thrombolysis [IVT] followed by
mechanical thrombectomy) is superior to IVT alone in minor stroke with large vessel …