Off-label use of intravenous thrombolysis for acute ischemic stroke: a critical appraisal of randomized and real-world evidence
G Tsivgoulis, O Kargiotis… - Therapeutic …, 2021 - journals.sagepub.com
Intravenous thrombolysis (IVT) represents the only systemic reperfusion therapy able to
reverse neurological deficit in patients with acute ischemic stroke (AIS). Despite its …
reverse neurological deficit in patients with acute ischemic stroke (AIS). Despite its …
Intravenous thrombolysis versus antiplatelet therapy in minor stroke patients with large vessel occlusion
Aim Our study aimed to explore the effectiveness and safety of intravenous t‐PA compared
with dual antiplatelet therapy (DAPT) and aspirin alone for minor stroke with National …
with dual antiplatelet therapy (DAPT) and aspirin alone for minor stroke with National …
StrokeClassifier: ischemic stroke etiology classification by ensemble consensus modeling using electronic health records
Determining acute ischemic stroke (AIS) etiology is fundamental to secondary stroke
prevention efforts but can be diagnostically challenging. We trained and validated an …
prevention efforts but can be diagnostically challenging. We trained and validated an …
Predictors of outcomes in patients with mild ischemic stroke symptoms: MaRISS
JG Romano, H Gardener, I Campo-Bustillo, Y Khan… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Although most strokes present with mild symptoms, these have
been poorly represented in clinical trials. The objective of this study is to describe …
been poorly represented in clinical trials. The objective of this study is to describe …
Redefined measure of early neurological improvement shows treatment benefit of alteplase over placebo
Background and Purpose—The first of the 2 NINDS (National Institute of Neurological
Disorders and Stroke) Study trials did not show a significant increase in early neurological …
Disorders and Stroke) Study trials did not show a significant increase in early neurological …
Pterostilbene alleviates abdominal aortic aneurysm via inhibiting macrophage pyroptosis by activating the miR-146a-5p/TRAF6 axis
H Cai, L Huang, M Wang, R Liu, J Qiu, Y Qin, X Yao… - Food & Function, 2024 - pubs.rsc.org
Pterostilbene (PTE), a natural stilbene found in blueberries and several varieties of grapes,
has several pharmacological activities, including anti-inflammatory and antioxidative …
has several pharmacological activities, including anti-inflammatory and antioxidative …
Updated trends, disparities, and clinical impact of neuroimaging utilization in ischemic stroke in the Medicare population: 2012 to 2019
JJ Wang, CE Pelzl, A Boltyenkov, JM Katz… - Journal of the American …, 2022 - Elsevier
Objective The purpose of this study was to update trends, investigate sociodemographic
disparities, and evaluate the impact on mortality of stroke neuroimaging across the United …
disparities, and evaluate the impact on mortality of stroke neuroimaging across the United …
[HTML][HTML] Using tenecteplase for acute ischemic stroke: what is the hold up?
T Zitek, R Ataya, I Brea - Western Journal of Emergency Medicine, 2020 - ncbi.nlm.nih.gov
Alteplase is the only Food and Drug Administration-approved intravenous (IV) thrombolytic
medication for acute ischemic stroke. However, multiple recent studies comparing …
medication for acute ischemic stroke. However, multiple recent studies comparing …
Chinese Stroke Association guidelines for clinical management of ischaemic cerebrovascular diseases: executive summary and 2023 update
L Liu, Z Li, H Zhou, W Duan, X Huo, W Xu… - Stroke and vascular …, 2023 - svn.bmj.com
Background China is one of the countries with the highest burden of stroke. Implementing
multidimensional management guidelines will help clinicians practise evidence-based care …
multidimensional management guidelines will help clinicians practise evidence-based care …
Perfusion imaging and clinical outcome in acute minor stroke with large vessel occlusion
P Seners, C Arquizan, L Fontaine, W Ben Hassen… - Stroke, 2022 - Am Heart Assoc
Background: Whether bridging therapy (intravenous thrombolysis [IVT] followed by
mechanical thrombectomy) is superior to IVT alone in minor stroke with large vessel …
mechanical thrombectomy) is superior to IVT alone in minor stroke with large vessel …