Statistical analyses of ordinal outcomes in randomised controlled trials: a scoping review

CJ Selman, KJ Lee, KN Ferguson, CL Whitehead… - Trials, 2024 - Springer
Abstract Background Randomised controlled trials (RCTs) aim to estimate the causal effect
of one or more interventions relative to a control. One type of outcome that can be of interest …

Structural and functional imaging of the retina in central retinal artery occlusion–current approaches and future directions

B Mac Grory, M Schrag, S Poli, CJ Boisvert… - Journal of Stroke and …, 2021 - Elsevier
Central retinal artery occlusion (CRAO) is a form of acute ischemic stroke which affects the
retina. Intravenous thrombolysis is emerging as a compelling therapeutic approach …

Clinical characteristics and in-hospital outcomes of varying definitions of minor stroke: from a large-scale nation-wide longitudinal registry

Y Xiong, H Gu, XQ Zhao, X Yang, C Wang, YL Wang… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: A variety of definitions for minor stroke have been proposed. We
aimed to compare the clinical characteristics and outcomes of minor stroke defined as the …

Associations of osteoarthritis with thrombectomy utilization and outcomes for large vessel acute ischemic stroke

H Chen, M Khunte, M Colasurdo, G Jindal, A Malhotra… - Stroke, 2023 - Am Heart Assoc
Background: Osteoarthritis and other musculoskeletal disorders are the leading causes of
disability in the United States. While osteoarthritis is not a direct risk factor for stroke …

Acute reperfusion therapies for acute ischemic stroke

R Imran, GA Mohamed, F Nahab - Journal of Clinical Medicine, 2021 - mdpi.com
The field of acute stroke treatment has made tremendous progress in reducing the overall
burden of disability. Understanding the pathophysiology of acute ischemic injury …

Intravenous Alteplase Versus Best Medical Therapy for Patients With Minor Stroke: A Systematic Review and Meta-Analysis

Y Zhang, T Lv, TN Nguyen, S Wu, Z Li, X Bai, D Chen… - Stroke, 2024 - Am Heart Assoc
BACKGROUND: The efficacy of thrombolysis (IVT) in minor stroke (National Institutes of
Health Stroke Scale score, 0–5) remains inconclusive. The aim of this study is to compare …

[HTML][HTML] An update on hyper-acute management of ischaemic stroke

A Bhalla, M Patel, J Birns - Clinical Medicine, 2021 - Elsevier
This article aims to provide a comprehensive overview of key advances on various aspects
of hyper-acute management of acute ischaemic stroke. These include neuroimaging, acute …

A Randomized Controlled Trial of Tenecteplase Versus Standard of Care for Minor Ischemic Stroke with Proven Occlusion (TEMPO-2): Rational and design of a …

N Singh, CC Kenney, KS Butcher… - … Journal of Stroke, 2024 - journals.sagepub.com
Background: Almost half of acute ischemic stroke patients present with mild symptoms and
there are large practice variations in their treatment globally. Individuals with an intracranial …

Intravenous alteplase in minor nondisabling ischemic stroke: a systematic review and meta-analysis

A Alhazzani, FS Al-Ajlan, A Alkhiri… - European Stroke …, 2024 - journals.sagepub.com
Background: Minor ischemic stroke, defined as National Institute of Health Stroke Scale
score of 0–5 on admission, represents half of all acute ischemic strokes. The role of …

MRI-based thrombolytic therapy in patients with acute ischemic stroke presenting with a low NIHSS

S Majidi, M Luby, JK Lynch, AW Hsia, RT Benson… - Neurology, 2019 - AAN Enterprises
Objective Treatment of patients with stroke presenting with minor deficits remains
controversial, and the recent Potential of rtPA for Ischemic Strokes with Mild Symptoms …