The VTA contains the A10 group of DA containing neurons. These neurons have been
grouped into nuclei to be found on the floor of the midbrain tegmentum—Npn, Nif, Npbp and …

Neurodegenerative diseases (NDs) represents debilitating conditions characterized by
degeneration of neuronal cells in specific brain areas, causing disability and death in …

Environmental toxicants and, in particular, pesticides have been implicated as risk factors in
Parkinson's disease (PD). The purpose of this study was to determine if selective …

An autoradiographic procedure has been used to determine the quantitative distributions of
γ-aminobutyric acid (GABA A and GABA B) receptor subtypes in rat brain. Although the …

Dopamine can be released in the substantia nigra from the dendrites of nigrostriatal
dopaminergic neurones, to be involved there in the self-regulation of the dopaminergic cells …

1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) damages dopaminergic neurons in
the substantia nigra pars compacta (SNpc) as seen in Parkinson's disease. Here, we show …

The effect of systemic and intracerebral injections of kainic acid, a potent neuroexcitatory
and neurotoxic analogue of glutamate, has been studied in the rat using a variety of light …

Methylenedioxymethamphetamine (MDMA or “Ecstasy”) was first synthesised 80 years ago,
but has recently received prominence as an illegally synthesised recreational drug of abuse …

1. Intracellular recordings were made from 193 substantia nigra zona compacta neurones in
slices of rat mesencephalon. All cells were hyperpolarized by baclofen; this was …

Following the injection of horseradish peroxidase into the ipsilaeral substantia nigra, 36
retrogradely labelled neurons in the striatum were characterized (in three rats) by Golgi …