Metal toxicity links to Alzheimer's disease and neuroinflammation

TJ Huat, J Camats-Perna, EA Newcombe… - Journal of molecular …, 2019 - Elsevier
As the median age of the population increases, the number of individuals with Alzheimer's
disease (AD) and the associated socio-economic burden are predicted to worsen. While …

[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism

T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Fluorescent chemosensors based on spiroring-opening of xanthenes and related derivatives

X Chen, T Pradhan, F Wang, JS Kim, J Yoon - Chemical reviews, 2012 - ACS Publications
The recognition and sensing of biologically and environmentally important species has
emerged as a significant goal in the field of chemical sensors in recent years. 1Ā10 Several …

Metal coordination in photoluminescent sensing

Z Liu, W He, Z Guo - Chemical Society Reviews, 2013 - pubs.rsc.org
Coordination chemistry plays an essential role in the design of photoluminescent probes for
metal ions. Metal coordination to organic dyes induces distinct optical responses which …

[HTML][HTML] The essential toxin: impact of zinc on human health

LM Plum, L Rink, H Haase - … journal of environmental research and public …, 2010 - mdpi.com
Compared to several other metal ions with similar chemical properties, zinc is relatively
harmless. Only exposure to high doses has toxic effects, making acute zinc intoxication a …

[HTML][HTML] Neuron-astrocyte interactions in Parkinson's disease

I Miyazaki, M Asanuma - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disease. PD
patients exhibit motor symptoms such as akinesia/bradykinesia, tremor, rigidity, and postural …

The glutamate receptor ion channels

R Dingledine, K Borges, D Bowie, SF Traynelis - Pharmacological reviews, 1999 - ASPET
The ionotropic glutamate receptors are ligand-gated ion channels that mediate the vast
majority of excitatory neurotransmission in the brain. The cloning of cDNAs encoding …

Review on recent advances in metal ions sensing using different fluorescent probes

S Chowdhury, B Rooj, A Dutta, U Mandal - Journal of fluorescence, 2018 - Springer
Fluorescence probes serves as unique detection methods for its simplicity and low detection
limit (LOD) and especially bioimaging ability. Research on the probes has already sprouted …

Fluorescent detection of zinc in biological systems: recent development on the design of chemosensors and biosensors

P Jiang, Z Guo - Coordination chemistry reviews, 2004 - Elsevier
Zinc is an essential biological element for living organisms and fluorescent imaging has
been proven to be the most suitable technique for its in vivo monitoring. From the late 1980s …

[HTML][HTML] Genetic and epigenetic etiology underlying autism spectrum disorder

SH Yoon, J Choi, WJ Lee, JT Do - Journal of clinical medicine, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterized
by difficulties in social interaction, language development delays, repeated body …