Various diseases remain untreated due to lack of suitable therapeutic moiety or a suitable
drug delivery device, especially where toxicities and side effects are the primary reason for …

Epidermal growth factor receptor (EGFR) is an anticancer drug target for a number of
cancers, such as non-small cell lung cancer. However, unsatisfying treatment effects, terrible …

Single‐atom nanozymes (SANzymes) emerge as promising alternatives to conventional
enzymes. However, chemical instability limits their application. Here, a systematic synthesis …

Nasopharyngeal carcinoma (NPC) has seen improved treatment outcomes and a decrease
in incidence worldwide in recent years due to developments in medicine and improved …

Hepatocellular carcinoma (HCC) is the sixth most commonly malignant tumor and the third
leading cause of cancer-related death in the world, and the early diagnosis and treatment of …

Cancer metastasis, the spread of disease from a primary to a distal site through the
circulatory or lymphatic systems, accounts for over 90% of all cancer related deaths. Despite …

Genomic instability facilitates the evolution of cells, tissues, organs, and species. The
progression of human malignancies can be regarded as the accumulation of genomic …

Background/Aim: Triple-negative breast cancer (TNBC) is an aggressive type of breast
cancer that still requires improvement in treatment. Magnolol extract, derived from the bark of …

Background Leptin is important in physiological and pathological functions in various
cancers, however, the significance and mechanisms of leptin in nasopharyngeal carcinoma …

A new series of 5-trifluoromethylpyrimidine derivatives were designed and synthesised as
EGFR inhibitors. Three tumour cells A549, MCF-7, PC-3 and EGFR kinase were employed …