Nanomedicine based approaches for combating viral infections

S Shah, MB Chougule, AK Kotha, R Kashikar… - Journal of Controlled …, 2021 - Elsevier
Millions of people die each year from viral infections across the globe. There is an urgent
need to overcome the existing gap and pitfalls of the current antiviral therapy which include …

Inhaled antibodies: Quality and performance considerations

AJ Hickey, IE Stewart - Human vaccines & immunotherapeutics, 2022 - Taylor & Francis
The use of antibodies in the treatment of lung diseases is of increasing interest especially as
the search for COVID-19 therapies has unfolded. Historically, the use of antibody therapy …

Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19

K Tiruthani, C Cruz‐Teran, JFW Chan… - Bioengineering & …, 2024 - Wiley Online Library
Soluble angiotensin‐converting enzyme 2 (ACE2) can act as a decoy molecule that
neutralizes severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) by blocking …

ZMapp reduces diffusion of Ebola viral particles in fresh human cervicovaginal mucus

A Schaefer, B Yang, HA Schroeder, D Harit… - Emerging Microbes & …, 2024 - Taylor & Francis
Vaginal transmission from semen of male Ebola virus (EBOV) survivors has been implicated
as a potential origin of Ebola virus disease (EVD) outbreaks. While EBOV in semen must …