Emergence, molecular mechanisms and global spread of carbapenem-resistant Acinetobacter baumannii

M Hamidian, SJ Nigro - Microbial genomics, 2019 - microbiologyresearch.org
Acinetobacter baumannii is a nosocomial pathogen that has emerged as a global threat
because of high levels of resistance to many antibiotics, particularly those considered to be …

Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

[HTML][HTML] Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside

MF Lin, CY Lan - World Journal of Clinical Cases: WJCC, 2014 - ncbi.nlm.nih.gov
Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

Diversity, epidemiology, and genetics of class D β-lactamases

L Poirel, T Naas, P Nordmann - Antimicrobial agents and …, 2010 - Am Soc Microbiol
Class D β-lactamase-mediated resistance to β-lactams has been increasingly reported
during the last decade. Those enzymes also known as oxacillinases or OXAs are widely …

Emerging carbapenemases: a global perspective

TR Walsh - International journal of antimicrobial agents, 2010 - Elsevier
The celestial rise in antibiotic resistance among Gram-negative bacteria has challenged
both the scientific and pharmaceutical sectors. The hallmark of this general increase is the …

[HTML][HTML] Worldwide dissemination of the blaOXA-23 Carbapenemase gene of Acinetobacter baumannii1

PD Mugnier, L Poirel, T Naas… - Emerging infectious …, 2010 - ncbi.nlm.nih.gov
To assess dissemination of OXA-23–producing strains of Acinetobacter baumannii, we
obtained 20 carbapenem-resistant, OXA-23–producing isolates from different regions. Their …

Carbapenemase-producing Gram-negative bacteria: current epidemics, antimicrobial susceptibility and treatment options

SS Jean, WS Lee, C Lam, CW Hsu, RJ Chen… - Future …, 2015 - Taylor & Francis
Carbapenemases, with versatile hydrolytic capacity against β-lactams, are now an important
cause of resistance of Gram-negative bacteria. The genes encoding for the acquired …

Complete Genome Analysis of Three Acinetobacter baumannii Clinical Isolates in China for Insight into the Diversification of Drug Resistance Elements

L Zhu, Z Yan, Z Zhang, Q Zhou, J Zhou, EK Wakeland… - PloS one, 2013 - journals.plos.org
Background The emergence and rapid spreading of multidrug-resistant Acinetobacter
baumannii strains has become a major health threat worldwide. To better understand the …

Phenotypic and Molecular Characteristics of Carbapenem-Resistant Acinetobacter baumannii Isolates from Bulgarian Intensive Care Unit Patients

TV Strateva, I Sirakov, TJ Stoeva, A Stratev, S Peykov - Microorganisms, 2023 - mdpi.com
Carbapenem-resistant Acinetobacter baumannii (CRAB) is designated as an urgent public
health threat, both due to its remarkable multidrug resistance and propensity for clonal …

Diversity of carbapenem resistance mechanisms in Acinetobacter baumannii from a Taiwan hospital: spread of plasmid-borne OXA-72 carbapenemase

PL Lu, M Doumith, DM Livermore… - Journal of …, 2009 - academic.oup.com
Objectives We investigated the molecular epidemiology of carbapenem-resistant
Acinetobacter baumannii from a Taiwanese hospital and determined the mechanisms …