Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency

H Zeng, L Cheng, D Lu, S Fan, K Wang, L Xu… - Journal of …, 2023 - Springer
Background Spinal cord injury (SCI), which causes loss of sensory and motor function in the
body below the level of injury, is a devastating disease of the central nervous system. SCI …

Systemic and pulmonary inflammation/oxidative damage: Implications of general and respiratory muscle training in chronic spinal-cord-injured patients

OF Araneda, C Rosales-Antequera… - Biology, 2023 - mdpi.com
Simple Summary Damage to the spinal cord affects the voluntary control of skeletal muscles
and also the control of the autonomic nervous system, thus affecting the cardiorespiratory …

Physically and Chemically Crosslinked Hyaluronic Acid-Based Hydrogels Differentially Promote Axonal Outgrowth from Neural Tissue Cultures

A Bajic, B Andersson, A Ossinger, S Tavakoli… - Biomimetics, 2024 - mdpi.com
Our aim was to investigate axonal outgrowth from different tissue models on soft
biomaterials based on hyaluronic acid (HA). We hypothesized that HA-based hydrogels …

Spinal Cord Injury: From MicroRNAs to Exosomal MicroRNAs

X Xu, R Liu, Y Li, C Zhang, C Guo, J Zhu, J Dong… - Molecular …, 2024 - Springer
Spinal cord injury (SCI) is an unfortunate experience that may generate extensive sensory
and motor disabilities due to the destruction and passing of nerve cells. MicroRNAs are …

bFGF-like Activity Supported Tissue Regeneration, Modulated Neuroinflammation, and Rebalanced Ca2+ Homeostasis following Spinal Cord Injury

A Ardizzone, V Bova, G Casili, A Filippone… - International Journal of …, 2023 - mdpi.com
A spinal cord injury (SCI) is a well-defined debilitating traumatic event to the spinal cord that
usually triggers permanent changes in motor, sensory, and autonomic functions. Injured …

Neutrophil-to-lymphocyte ratio at admission for early diagnosis, severity assessment, and prognosis of acute traumatic spinal cord injury

X Chen, Y Zhou, C Chen, Y Cao - Spinal Cord, 2024 - nature.com
Study design A retrospective study. Objective This study examined the value of neutrophil-to-
lymphocyte ratio at admission for early diagnosis, severity assessment, and prognosis of …

MSR405: Inhibiting Neuroinflammation after Spinal Cord Injury in Rats

Y Liu, Y Xiao, J Gao, J Gao, R Li, Z Qi, X Liu - Biomedicines, 2024 - mdpi.com
The treatment of spinal cord injury (SCI) is often ineffective. Additionally, SCI-induced
inflammation leads to secondary injury. Current anti-inflammatory hydrophilic drugs fail to …

Screening biomarkers for spinal cord injury using weighted gene co-expression network analysis and machine learning

X Li, Y Yang, S Xu, Y Gui, J Chen… - Neural Regeneration …, 2024 - journals.lww.com
Immune changes and inflammatory responses have been identified as central events in the
pathological process of spinal cord injury. They can greatly affect nerve regeneration and …

Perioperatives Management nach traumatischer Querschnittslähmung

A Heuer, LG Koepke, L Viezens, M Schroeder - Die Unfallchirurgie, 2023 - Springer
Dieser Beitrag beschreibt den aktuellen Stand der Behandlung traumatischer
Rückenmarkverletzungen mit dem Fokus auf die perioperative Phase. Es werden …

Glucagon-like peptide-1 influences proliferation within the spinal cord; an effect via cerebrospinal fluid contacting neurons?

MHM Clark - 2023 - etheses.whiterose.ac.uk
The influence of glucagon-like peptide-1 (GLP-1) on CNS functions, such as neurogenesis,
neuroprotection, and anti-neuroinflammation, prompted investigation into its role in spinal …