An open question in the field is to define the mechanistic underpinning of why glymphatic
function is suppressed. Other questions include the opportunities for using glymphatic …

Clearance of neurotoxic brain proteins via cerebrospinal fluid (CSF) to blood has recently
emerged to be crucial, and plasma biomarkers of neurodegeneration were newly introduced …

The glymphatic system is a newly discovered waste-clearing system that is analogous to the
lymphatic system in our central nervous system. Furthermore, disruption in the glymphatic …

The ocular glymphatic system supports bidirectional fluid transport along the optic nerve,
thereby removes metabolic wastes including amyloid-β. To better understand this biological …

Purpose The present study investigates a multimodal imaging assessment of glymphatic
function and its association with brain amyloid-beta deposition. Methods Two brain CSF …

Over the last decade, it has become evident that cerebrospinal fluid (CSF) plays a pivotal
role in brain solute clearance through perivascular pathways and interactions between the …

Background Impaired glymphatic clearance of cerebral metabolic products and fluids
contribute to traumatic and ischemic brain oedema and neurodegeneration in preclinical …

Objective Solute transport in the brain is essential for maintaining cerebral homeostasis.
Recent studies have shown that neuronal activity enhances the transport of cerebrospinal …

Dominance of Tau Burden in Cortical Over Subcortical Regions... : Clinical Nuclear Medicine
Dominance of Tau Burden in Cortical Over Subcortical Regions Mediates Glymphatic Activity …

Purpose: To investigate if glymphatic clearance function assessed by multimodality imaging
can improve the prediction of brain beta amyloid deposition. Methods: Two brain CSF …