A SPECT-based method for dynamic imaging of the glymphatic system in rats

B Sigurdsson, NL Hauglund, TO Lilius… - Journal of Cerebral …, 2023 - journals.sagepub.com
The glymphatic system is a brain-wide waste drainage system that promotes cerebrospinal
fluid circulation through the brain to remove waste metabolites. Currently, the most common …

Peptide-based nanoassemblies in gene therapy and diagnosis: paving the way for clinical application

S Tarvirdipour, X Huang, V Mihali, CA Schoenenberger… - Molecules, 2020 - mdpi.com
Nanotechnology approaches play an important role in developing novel and efficient
carriers for biomedical applications. Peptides are particularly appealing to generate such …

Preclinical imaging: an essential ally in modern biosciences

L Cunha, I Horvath, S Ferreira, J Lemos… - Molecular diagnosis & …, 2014 - Springer
Translational research is changing the practice of modern medicine and the way in which
health problems are approached and solved. The use of small-animal models in basic and …

Luminescence-based imaging approaches in the field of interventional molecular imaging

FWB van Leeuwen, JCH Hardwick, AR van Erkel - Radiology, 2015 - pubs.rsna.org
Luminescence imaging–based guidance technologies are increasingly gaining interest
within surgical and radiologic disciplines. Their promise to help visualize molecular features …

State of the art in vivo imaging techniques for laboratory animals

DT Lauber, A Fülöp, T Kovács, K Szigeti… - Laboratory …, 2017 - journals.sagepub.com
In recent decades, imaging devices have become indispensable tools in the basic sciences,
in preclinical research and in modern drug development. The rapidly evolving high …

Tracers and imaging of fatty acid and energy metabolism of human adipose tissues

AC Carpentier - Physiology, 2024 - journals.physiology.org
White adipose tissue and brown adipose tissue (WAT and BAT) regulate fatty acid
metabolism and control lipid fluxes to other organs. Dysfunction of these key metabolic …

[HTML][HTML] Positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging of macrophages in large vessel vasculitis: current …

WF Jiemy, P Heeringa, JAAM Kamps… - Autoimmunity …, 2018 - Elsevier
Macrophages are key players in the pathogenesis of large-vessel vasculitis (LVV) and may
serve as a target for diagnostic imaging of LVV. The radiotracer, 18 F-FDG has proven to be …

Multimodal tumor-targeting peptides functionalized with both a radio-and a fluorescent label

J Kuil, AH Velders, FWB van Leeuwen - Bioconjugate chemistry, 2010 - ACS Publications
The use of monolabeled tumor-targeting peptides for molecular imaging is widespread.
However, it is often desirable to use the same compound for different clinical applications …

In vivo detection of cucurbit[6]uril, a hyperpolarized xenon contrast agent for a xenon magnetic resonance imaging biosensor

FT Hane, T Li, P Smylie, RM Pellizzari, JA Plata… - Scientific Reports, 2017 - nature.com
Abstract The Hyperpolarized gas Chemical Exchange Saturation Transfer (HyperCEST)
Magnetic Resonance (MR) technique has the potential to increase the sensitivity of a …

Hybrid imaging: instrumentation and data processing

J Cal-Gonzalez, I Rausch, LK Shiyam Sundar… - Frontiers in …, 2018 - frontiersin.org
State-of-the-art patient management frequently requires the use of non-invasive imaging
methods to assess the anatomy, function or molecular-biological conditions of patients or …