Gliomas are complex and heterogeneous brain tumors with poor prognosis. Glioma cells
can communicate with their surroundings to create a tumor-permissive microenvironment …

Radiographic endpoints including response and progression are important for the
evaluation of new glioblastoma therapies. The current RANO criteria was developed to …

Summary Background The Response Assessment in Neuro-Oncology (RANO) criteria and
requirements for a uniform protocol have been introduced to standardise assessment of MRI …

Background Concurrent treatment with temozolomide and radiotherapy followed by
maintenance temozolomide is the standard of care for patients with newly diagnosed …

Despite having an abundant number of vessels, tumours are usually hypoxic and nutrient-
deprived because their vessels malfunction. Such abnormal milieu can fuel disease …

Currently, the most widely used criteria for assessing response to therapy in high-grade
gliomas are based on two-dimensional tumor measurements on computed tomography (CT) …

Current therapy of malignant glioma in clinic is unsatisfactory with poor patient compliance
due to low therapeutic efficiency and strong systemic side effects. Herein, we combined …

Inside the Sixth Edition of this now-classic reference, you will discover encyclopedic
coverage of topics ranging from basic science to sophisticated computer-based radiation …

The current standard of care for newly diagnosed cases of high-grade glioma is surgical
resection followed by RT with concurrent chemotherapy. The most widely used criteria for …

Glioblastoma cells secrete extra-cellular vesicles (EVs) containing microRNAs (miRNAs).
Analysis of these EV miRNAs in the bio-fluids of afflicted patients represents a potential …