Red meat and processed meat consumption has been hypothesized to increase risk of
cancer, but the evidence is inconsistent. We performed a systematic review and meta …

Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …

Obesity and its repercussions constitute an important source of morbidity, impaired quality of
life and its complications can have a major bearing on life expectancy. The present article …

In sharp contrast to many other cancer types, the incidence and mortality of endometrial
cancer continue to grow. This unfortunate trend is, in no small part, a result of the worldwide …

Aging is the inevitable time-dependent decline in physiological organ function and is a
major risk factor for cancer development. Due to advances in health care, hygiene control …

Adipose tissue influences tumor development in two major ways. First, obese individuals
have a higher risk of developing certain cancers (endometrial, esophageal, and renal cell …

Gene expression data are accumulating exponentially in public repositories. Reanalysis and
integration of themed collections from these studies may provide new insights, but requires …

Metformin is the most commonly prescribed drug for type 2 diabetes (T2DM). Retrospective
studies show that metformin is associated with decreased cancer risk. This historical …

Endometrial cancer (EC) is a deleterious condition which strongly affects a woman's quality
of life. Although aggressive interventions should be considered to treat high-grade EC, a …

Background Polycystic ovary syndrome (PCOS) is one of the most common
endocrinopathies affecting reproductive‐aged women with adverse reproductive, metabolic …