Carboranes in drug discovery, chemical biology and molecular imaging
A Marfavi, P Kavianpour, LM Rendina - Nature Reviews Chemistry, 2022 - nature.com
There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …
Comparison of anticancer drug toxicities: paradigm shift in adverse effect profile
D Basak, S Arrighi, Y Darwiche, S Deb - Life, 2021 - mdpi.com
The inception of cancer treatment with chemotherapeutics began in the 1940s with nitrogen
mustards that were initially employed as weapons in World War II. Since then, treatment …
mustards that were initially employed as weapons in World War II. Since then, treatment …
Muscle wasting and sarcopenia in heart failure—the current state of science
A Lena, MS Anker, J Springer - International journal of molecular sciences, 2020 - mdpi.com
Sarcopenia is primarily characterized by skeletal muscle disturbances such as loss of
muscle mass, quality, strength, and physical performance. It is commonly seen in elderly …
muscle mass, quality, strength, and physical performance. It is commonly seen in elderly …
Phthalate toxicity mechanisms: An update
CG Sree, V Buddolla, BA Lakshmi, YJ Kim - Comparative Biochemistry and …, 2023 - Elsevier
Phthalates are one of the most widely used plasticizers in polymer products, and they are
increasingly being exposed to people all over the world, generating health concerns …
increasingly being exposed to people all over the world, generating health concerns …
The role of androgens in women's health and wellbeing
VE Bianchi, E Bresciani, R Meanti, L Rizzi… - Pharmacological …, 2021 - Elsevier
Androgens in women, as well as in men, are intrinsic to maintenance of (i) reproductive
competency,(ii) cardiac health,(iii) appropriate bone remodeling and mass retention,(iii) …
competency,(ii) cardiac health,(iii) appropriate bone remodeling and mass retention,(iii) …
Understanding and managing the suppression of spermatogenesis caused by testosterone replacement therapy (TRT) and anabolic–androgenic steroids (AAS)
A Desai, M Yassin, A Cayetano… - Therapeutic …, 2022 - journals.sagepub.com
Use of testosterone replacement therapy (TRT) and anabolic–androgenic steroids (AAS)
has increased over the last 20 years, coinciding with an increase in men presenting with …
has increased over the last 20 years, coinciding with an increase in men presenting with …
Newly developed targeted therapies against the androgen receptor in triple-negative breast cancer: A review
Among different types of breast cancers (BC), triple-negative BC (TNBC) amounts to 15% to
20% of breast malignancies. Three principal characteristics of TNBC cells are (i) extreme …
20% of breast malignancies. Three principal characteristics of TNBC cells are (i) extreme …
[图书][B] Applied animal endocrinology
EJ Squires - 2024 - cabidigitallibrary.org
This book explains the role of hormones in improving and monitoring the production,
performance, reproduction, behaviour and health of livestock animals, focusing on cattle …
performance, reproduction, behaviour and health of livestock animals, focusing on cattle …
The association between sarcopenia and diabetes: from pathophysiology mechanism to therapeutic strategy
H Chen, X Huang, M Dong, S Wen… - … Syndrome and Obesity, 2023 - Taylor & Francis
Diabetes and sarcopenia are emerging as serious public health issues. Sarcopenia, an age-
related disorder characterized by loss of skeletal muscle mass and function, is recognized …
related disorder characterized by loss of skeletal muscle mass and function, is recognized …
[HTML][HTML] Selective androgen receptor modulators: the future of androgen therapy?
AR Christiansen, LI Lipshultz, JM Hotaling… - Translational …, 2020 - ncbi.nlm.nih.gov
Selective androgen receptor modulators (SARMs) are small molecule drugs that function as
either androgen receptor (AR) agonists or antagonists. Variability in AR regulatory proteins …
either androgen receptor (AR) agonists or antagonists. Variability in AR regulatory proteins …