[HTML][HTML] Selective androgen receptor modulators: an emerging liver toxin

H Mohideen, H Hussain, DS Dahiya… - Journal of Clinical and …, 2023 - ncbi.nlm.nih.gov
Selective androgen receptor modulators (SARMs) are a class of nonsteroidal drugs that are
favored over anabolic androgenic steroids (AASs) for their tissue-selectivity and improved …

Overview of the development of selective androgen receptor modulators (SARMs) as pharmacological treatment for osteoporosis (1998–2021)

Y Xie, Y Tian, Y Zhang, Z Zhang, R Chen, M Li… - European journal of …, 2022 - Elsevier
Osteoporosis is a common disease in which the risk of fracture increases due to decreased
bone mass and qualitative skeletal changes. Selective androgen receptor modulators …

[HTML][HTML] Need for Sexual, Reproductive, and Mental Health Promotion Among Diverse College Students in a COVID-19 Era

M Cooley-Strickland, GE Wyatt, TB Loeb… - Clinical Child and …, 2023 - Springer
Abstract In 2020, the COVID-19 pandemic forced unprecedented disruptions in higher
education operations. While the adverse mental health effects experienced by college …

[HTML][HTML] Ligandrol (LGD-4033)-induced liver injury

M Barbara, S Dhingra, AL Mindikoglu - ACG case reports journal, 2020 - journals.lww.com
We described a 32-year-old man who developed severe drug-induced liver injury after using
Ligandrol (LGD-4033). The diagnosis was confirmed by a liver biopsy that showed …

Performance‐enhancing drugs and the Olympics

CJ Watson, GL Stone, DL Overbeek… - Journal of Internal …, 2022 - Wiley Online Library
The rules of fair play in sport generally prohibit the use of performance‐enhancing drugs
(PEDs). The World Anti‐Doping Agency (WADA) oversees global antidoping regulations …

[HTML][HTML] Clinical implications of androgen-positive triple-negative breast cancer

M Brumec, M Sobočan, I Takač, D Arko - Cancers, 2021 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) represents a heterogeneous group
of breast cancers that lack estrogen receptor (ER), progesterone receptor (PR), and human …

Use, misuse and abuse of testosterone and other androgens

BL Linhares, EP Miranda, AR Cintra… - Sexual medicine …, 2022 - academic.oup.com
Introduction For several decades, testosterone and its synthetic derivatives have been used
for anabolic and androgenic purposes. Initially restricted to professional bodybuilders, these …

Psychosocial aspects of sports medicine in pediatric athletes: Current concepts in the 21st century

DE Greydanus, B Ergun-Longmire, MD Cabral… - Disease-a-Month, 2023 - Elsevier
Behavioral aspects of organized sports activity for pediatric athletes are considered in a
world consumed with winning at all costs. In the first part of this treatise, we deal with a …

Targeting androgen receptor for prostate cancer therapy: From small molecules to PROTACs

I Avgeris, D Pliatsika, SS Nikolaropoulos… - Bioorganic …, 2022 - Elsevier
Prostate cancer (PCa) remains a serious type of cancer for men worldwide. The majority of
new PCa cases are associated with androgen receptor (AR) hyperactivity. Various AR …

Testing anabolic activity, potency and mechanisms of action of the phyto-derived beta 2 agonist higenamine

L Jiang, M Piribauer, T Kostov, S Steidel, DA Bizjak… - Toxicology Letters, 2023 - Elsevier
Higenamine (Hige), a plant derived alkaloid is classified as β2 agonist by the World Anti-
Doping Agency (WADA). However, pharmacologic mechanisms of its performance …