The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …

Cytomegalovirus (CMV) infection is a significant complication in hematopoietic cell
transplantation (HCT) recipients. Four antiviral drugs are used for preventing or treating …

PURPOSE: To assess the efficacy of intravitreous fomivirsen sodium, an antisense
oligonucleotide, for newly diagnosed peripheral cytomegalovirus (CMV) retinitis in patients …

Human cytomegalovirus (HCMV) infection is a major cause of morbidity and mortality in
allogeneic hematopoietic stem cell transplant recipients. The significant clinical impact of …

In pediatric and adult patients after stem cell transplantation (SCT) disseminated infections
caused by human cytomegalovirus (HCMV) can cause life threatening diseases. For …

ABSTRACT A strain of human cytomegalovirus, T2211, modified from standard laboratory
strain AD169 to contain a secreted alkaline phosphatase reporter gene for rapid viral …

purpose. To perform a detailed pharmacokinetic study and to evaluate the drug levels
reached in the retina after the intravitreal administration of ganciclovir and foscarnet to …

The incidence of human cytomegalovirus (HCMV) disease in AIDS patients decreased
dramatically after the introduction, a few years ago, of highly active antiretroviral combination …

DNA viruses, as well as their host cells, require a DNA-dependent DNA polymerase to
faithfully replicate their genomes. Viruses with small DNA genomes, such as …

Human cytomegalovirus (HCMV) remains one of the major pathogens in
immunocompromised patients (AIDS and transplants) and the main cause for congenital …