Epigenetic markers are potential biomarkers for diabetes and related complications. Using a
prospective cohort from the Hong Kong Diabetes Register, we perform two independent …

Diabetic kidney disease (DKD) is a severe diabetic complication that affects up to half of the
individuals with diabetes. Elevated blood glucose levels are a key underlying cause of DKD …

Chronic kidney disease is a major public health burden. Elevated urinary albumin-to-
creatinine ratio is a measure of kidney damage, and used to diagnose and stage chronic …

Exposure to perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) is
associated with blood lipids in adults, but the underlying mechanisms remain unclear. This …

The prevalence of diabetes is increasing globally, and this trend is predicted to continue for
future decades. Research is needed to uncover new ways to manage diabetes and its co …

Background A subset of individuals with type 1 diabetes mellitus (T1DM) are predisposed to
developing diabetic kidney disease (DKD), the most common cause globally of end-stage …

Diabetic kidney disease (DKD) represents a major global health problem. Accelerated
ageing is a key feature of DKD and, therefore, characteristics of accelerated ageing may …

Although there are some epigenome-wide association studies (EWAS) of insulin resistance,
for most of them authors did not replicate their findings, and most are focused on populations …

Variation in DNA methylation (DNAmet) in white blood cells and other cells/tissues has been
implicated in the etiology of progressive diabetic kidney disease (DKD). However, the …

Background The potential for DNA methylation (DNAm) as an early marker for
cardiovascular disease (CVD) and how such an association might differ by glycemic …