Targeting Nrf2 signaling pathway by quercetin in the prevention and treatment of neurological disorders: An overview and update on new developments
MY Zamanian, A Soltani, Z Khodarahmi… - Fundamental & …, 2023 - Wiley Online Library
Abstract Background: Neurological disorders (NLDs) are widely acknowledged as a
significant public health concern worldwide. Stroke, Alzheimer's disease (AD), and traumatic …
significant public health concern worldwide. Stroke, Alzheimer's disease (AD), and traumatic …
Viral-based animal models in polyglutamine disorders
C Henriques, MM Lopes, AC Silva, DD Lobo, RA Badin… - Brain, 2024 - academic.oup.com
Polyglutamine disorders are a complex group of incurable neurodegenerative disorders
caused by an abnormal expansion in the trinucleotide cytosine-adenine-guanine tract of the …
caused by an abnormal expansion in the trinucleotide cytosine-adenine-guanine tract of the …
[HTML][HTML] AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b−/− Grn−/− mice
T Feng, G Minevich, P Liu, HX Qin, G Wozniak, J Pham… - Iscience, 2023 - cell.com
Loss of function of progranulin (PGRN), encoded by the granulin (GRN) gene, is implicated
in several neurodegenerative diseases. Several therapeutics to boost PGRN levels are …
in several neurodegenerative diseases. Several therapeutics to boost PGRN levels are …
[HTML][HTML] Novel chemical tyrosine functionalization of adeno-associated virus improves gene transfer efficiency in liver and retina
A Leray, PA Lalys, J Varin, M Bouzelha… - Biomedicine & …, 2024 - Elsevier
Decades of biological and clinical research have led to important advances in recombinant
adeno-associated viruses rAAV-based gene therapy gene therapy. However, several …
adeno-associated viruses rAAV-based gene therapy gene therapy. However, several …
Need of orthogonal approaches in neurological disease modeling in mouse
L Bossini, A Sessa - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Over the years, advancements in modeling neurological diseases have revealed innovative
strategies aimed at gaining deeper insights and developing more effective treatments for …
strategies aimed at gaining deeper insights and developing more effective treatments for …
[HTML][HTML] Efficient AAV9 Purification Using a Single-Step AAV9 Magnetic Affinity Beads Isolation
KC Sia, ZY Fu, SH Mohd Rodhi, JHY Yee, K Qu… - International Journal of …, 2024 - mdpi.com
Adeno-associated viruses (AAVs) have emerged as promising tools for gene therapy due to
their safety and efficacy in delivering therapeutic genes or gene editing sequences to …
their safety and efficacy in delivering therapeutic genes or gene editing sequences to …
[PDF][PDF] Targeting Nrf2 signaling pathway by quercetin in the prevention and treatment of neurological disorders: An overview and update on new developments
RF Obaid - researchgate.net
Neurological disorders (NLDs) are widely acknowledged as a significant public health
concern worldwide. Stroke, Alzheimer's disease (AD), and traumatic brain injury (TBI) are …
concern worldwide. Stroke, Alzheimer's disease (AD), and traumatic brain injury (TBI) are …