[HTML][HTML] The anti-VEGF (R) drug discovery legacy: improving attrition rates by breaking the vicious cycle of angiogenesis in cancer

D Ribatti, AG Solimando, F Pezzella - Cancers, 2021 - mdpi.com
Simple Summary Several anti-angiogenic drugs have been approved for cancer treatment,
alone or in combination with other anti-tumoral agents. Angiogenesis inhibitors cause drug …

Microneedles for gene and drug delivery in skin cancer therapy

D Zhi, T Yang, T Zhang, M Yang, S Zhang… - Journal of Controlled …, 2021 - Elsevier
The success of skin cancer treatment is severely limited in the route of administration
because most genes and drugs cannot break through the excellent stratum corneum (SC) …

Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses

M Wang, B Rousseau, K Qiu, G Huang, Y Zhang… - Nature …, 2023 - nature.com
Increasing evidence implicates the tumor microbiota as a factor that can influence cancer
progression. In patients with colorectal cancer (CRC), we found that pre-resection antibiotics …

[HTML][HTML] Magnetic particle imaging: An emerging modality with prospects in diagnosis, targeting and therapy of cancer

ZW Tay, P Chandrasekharan, BD Fellows… - Cancers, 2021 - mdpi.com
Simple Summary Magnetic Particle Imaging (MPI) is an emerging imaging technique that
provides quantitative direct imaging of superparamagnetic iron oxide nanoparticles. In the …

[HTML][HTML] Unboxing the molecular modalities of mutagens in cancer

S Kumari, S Sharma, D Advani, A Khosla… - … Science and Pollution …, 2021 - Springer
The etiology of the majority of human cancers is associated with a myriad of environmental
causes, including physical, chemical, and biological factors. DNA damage induced by such …

Recent progress in the synergistic combination of nanoparticle‐mediated hyperthermia and immunotherapy for treatment of cancer

ZR Stephen, M Zhang - Advanced healthcare materials, 2021 - Wiley Online Library
Immunotherapy has demonstrated great clinical success in certain cancers, driven primarily
by immune checkpoint blockade and adoptive cell therapies. Immunotherapy can elicit …

Dendritic cell vaccines improve the glioma microenvironment: Influence, challenges, and future directions

J Zhou, L Li, M Jia, Q Liao, G Peng, G Luo… - Cancer …, 2023 - Wiley Online Library
Introduction Gliomas, especially the glioblastomas, are one of the most aggressive
intracranial tumors with poor prognosis. This might be explained by the heterogeneity of …

Nanovaccines in cancer immunotherapy: Focusing on dendritic cell targeting

H Achmad, YS Ibrahim, MM Al-Taee, GA Gabr… - International …, 2022 - Elsevier
Cancer immunotherapy is proposed to eradicate tumors by stimulating host anti-tumor
immunity through utilizing various therapeutic approaches. Cancer vaccines have become a …

[HTML][HTML] Emerging avenues in immunotherapy for the management of malignant pleural mesothelioma

SG Gray - BMC Pulmonary Medicine, 2021 - Springer
Background The role of immunotherapy in cancer is now well-established, and therapeutic
options such as checkpoint inhibitors are increasingly being approved in many cancers such …

[HTML][HTML] Potential crosstalk between pericytes and cathepsins in the tumour microenvironment

A Mustafa, F Elkhamisy, N Arghiani… - Biomedicine & …, 2023 - Elsevier
Cancer remains a formidable global health challenge, and as such, investigators are
constantly exploring underlying mechanisms that drive its progression. One area of interest …