[HTML][HTML] The anti-VEGF (R) drug discovery legacy: improving attrition rates by breaking the vicious cycle of angiogenesis in cancer
Simple Summary Several anti-angiogenic drugs have been approved for cancer treatment,
alone or in combination with other anti-tumoral agents. Angiogenesis inhibitors cause drug …
alone or in combination with other anti-tumoral agents. Angiogenesis inhibitors cause drug …
Microneedles for gene and drug delivery in skin cancer therapy
D Zhi, T Yang, T Zhang, M Yang, S Zhang… - Journal of Controlled …, 2021 - Elsevier
The success of skin cancer treatment is severely limited in the route of administration
because most genes and drugs cannot break through the excellent stratum corneum (SC) …
because most genes and drugs cannot break through the excellent stratum corneum (SC) …
Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses
Increasing evidence implicates the tumor microbiota as a factor that can influence cancer
progression. In patients with colorectal cancer (CRC), we found that pre-resection antibiotics …
progression. In patients with colorectal cancer (CRC), we found that pre-resection antibiotics …
[HTML][HTML] Magnetic particle imaging: An emerging modality with prospects in diagnosis, targeting and therapy of cancer
Simple Summary Magnetic Particle Imaging (MPI) is an emerging imaging technique that
provides quantitative direct imaging of superparamagnetic iron oxide nanoparticles. In the …
provides quantitative direct imaging of superparamagnetic iron oxide nanoparticles. In the …
[HTML][HTML] Unboxing the molecular modalities of mutagens in cancer
The etiology of the majority of human cancers is associated with a myriad of environmental
causes, including physical, chemical, and biological factors. DNA damage induced by such …
causes, including physical, chemical, and biological factors. DNA damage induced by such …
Recent progress in the synergistic combination of nanoparticle‐mediated hyperthermia and immunotherapy for treatment of cancer
ZR Stephen, M Zhang - Advanced healthcare materials, 2021 - Wiley Online Library
Immunotherapy has demonstrated great clinical success in certain cancers, driven primarily
by immune checkpoint blockade and adoptive cell therapies. Immunotherapy can elicit …
by immune checkpoint blockade and adoptive cell therapies. Immunotherapy can elicit …
Dendritic cell vaccines improve the glioma microenvironment: Influence, challenges, and future directions
J Zhou, L Li, M Jia, Q Liao, G Peng, G Luo… - Cancer …, 2023 - Wiley Online Library
Introduction Gliomas, especially the glioblastomas, are one of the most aggressive
intracranial tumors with poor prognosis. This might be explained by the heterogeneity of …
intracranial tumors with poor prognosis. This might be explained by the heterogeneity of …
Nanovaccines in cancer immunotherapy: Focusing on dendritic cell targeting
Cancer immunotherapy is proposed to eradicate tumors by stimulating host anti-tumor
immunity through utilizing various therapeutic approaches. Cancer vaccines have become a …
immunity through utilizing various therapeutic approaches. Cancer vaccines have become a …
[HTML][HTML] Emerging avenues in immunotherapy for the management of malignant pleural mesothelioma
SG Gray - BMC Pulmonary Medicine, 2021 - Springer
Background The role of immunotherapy in cancer is now well-established, and therapeutic
options such as checkpoint inhibitors are increasingly being approved in many cancers such …
options such as checkpoint inhibitors are increasingly being approved in many cancers such …
[HTML][HTML] Potential crosstalk between pericytes and cathepsins in the tumour microenvironment
A Mustafa, F Elkhamisy, N Arghiani… - Biomedicine & …, 2023 - Elsevier
Cancer remains a formidable global health challenge, and as such, investigators are
constantly exploring underlying mechanisms that drive its progression. One area of interest …
constantly exploring underlying mechanisms that drive its progression. One area of interest …