[HTML][HTML] Shared aetiology underlying multiple sclerosis and other immune mediated inflammatory diseases: Swedish familial co-aggregation and large-scale genetic …

Q Liu, Y Jiang, T Frisell, P Stridh, K Shchetynsky… - Journal of …, 2024 - Elsevier
Background While multiple sclerosis (MS) affects less than 1% of the general population,
immune mediated inflammatory diseases (IMIDs) collectively influence 5–10% of the …

Mapping the genetic landscape of disorders on the autoimmune-autoinflammatory continuum: potential implications for classification and treatment

V Fominykh, AA Shadrin, P Jaholkowski, J Fuhrer… - medRxiv, 2024 - medrxiv.org
Objectives: Based on clinical, biomarker and genetic data, autoimmune and
autoinflammatory disorders (AIDs) can be classified as a disease continuum from pure …

Probing the basis of disease heterogeneity in multiple sclerosis using genetically diverse mice

EA Holt, A Tyler, T Lakusta-Wong, KG Lahue… - bioRxiv, 2024 - biorxiv.org
Multiple sclerosis (MS) is a complex disease with significant heterogeneity in disease course
and progression. Genetic studies have identified numerous loci associated with MS risk, but …

Immunogenetics of neurological disease

PL De Jager - Rosenberg's Molecular and Genetic Basis of …, 2025 - Elsevier
The study of immune and nervous system traits has been prominent throughout the course
of human genetic studies, and the interface of these two disciplines has had a profound …