[HTML][HTML] Human viruses and cancer

A Morales-Sánchez, EM Fuentes-Pananá - Viruses, 2014 - mdpi.com
The first human tumor virus was discovered in the middle of the last century by Anthony
Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt's lymphoma …

Castleman disease: the great mimic

D Bonekamp, KM Horton, RH Hruban, EK Fishman - Radiographics, 2011 - pubs.rsna.org
Castleman disease is a nonclonal lymphoproliferative disorder and one of the more
common causes of nonneoplastic lymphadenopathy. Because of its diverse manifestations …

Cell cycle regulation during viral infection

S Bagga, MJ Bouchard - Cell Cycle Control: Mechanisms and Protocols, 2014 - Springer
To replicate their genomes in cells and generate new progeny, viruses typically require
factors provided by the cells that they have infected. Subversion of the cellular machinery …

[HTML][HTML] The role of gammaherpesviruses in cancer pathogenesis

HC Jha, S Banerjee, ES Robertson - Pathogens, 2016 - mdpi.com
Worldwide, one fifth of cancers in the population are associated with viral infections. Among
them, gammaherpesvirus, specifically HHV4 (EBV) and HHV8 (KSHV), are two oncogenic …

[HTML][HTML] KSHV LANA—the master regulator of KSHV latency

T Uppal, S Banerjee, Z Sun, SC Verma, ES Robertson - Viruses, 2014 - mdpi.com
Kaposi's sarcoma associated herpesvirus (KSHV), like other human herpes viruses,
establishes a biphasic life cycle referred to as dormant or latent, and productive or lytic …

[HTML][HTML] MxB is an interferon-induced restriction factor of human herpesviruses

M Crameri, M Bauer, N Caduff, R Walker… - Nature …, 2018 - nature.com
The type I interferon (IFN) system plays an important role in controlling herpesvirus
infections, but it is unclear which IFN-mediated effectors interfere with herpesvirus …

[HTML][HTML] Molecular biology of KSHV lytic reactivation

P Purushothaman, T Uppal, SC Verma - Viruses, 2015 - mdpi.com
Kaposi's sarcoma-associated herpesvirus (KSHV) primarily persists as a latent episome in
infected cells. During latent infection, only a limited number of viral genes are expressed that …

[HTML][HTML] Towards better understanding of KSHV life cycle: from transcription and posttranscriptional regulations to pathogenesis

L Yan, V Majerciak, ZM Zheng, K Lan - Virologica Sinica, 2019 - Springer
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …

[HTML][HTML] Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells

O Yogev, D Lagos, T Enver, C Boshoff - PLoS pathogens, 2014 - journals.plos.org
Altered cell metabolism is inherently connected with pathological conditions including
cancer and viral infections. Kaposi's sarcoma-associated herpesvirus (KSHV) is the …

[HTML][HTML] KSHV genome replication and maintenance

P Purushothaman, P Dabral, N Gupta… - Frontiers in …, 2016 - frontiersin.org
Kaposi's sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a
major etiological agent for multiple severe malignancies in immune-compromised patients …