Onco-Pathogen mediated cancer progression and associated signaling pathways in cancer development

S Kannampuzha, AV Gopalakrishnan, H Padinharayil… - Pathogens, 2023 - mdpi.com
Infection with viruses, bacteria, and parasites are thought to be the underlying cause of
about 8–17% of the world's cancer burden, ie, approximately one in every five malignancies …

Non-HIV Kaposi's sarcoma: a review and therapeutic perspectives

Y Akasbi, A Awada, S Arifi, N Mellas, O El Mesbahi - Bulletin du cancer, 2012 - Elsevier
Abstract “Classic” Kaposi's sarcoma (CKS) not related to HIV is a multifocal
angioproliferative neoplasm that is linked to human herpesvirus. CKS is a cutaneous cancer …

[HTML][HTML] Delineation of a core RNA element required for Kaposi's sarcoma-associated herpesvirus ORF57 binding and activity

E Sei, NK Conrad - Virology, 2011 - Elsevier
The Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 protein is an essential
multifunctional regulator of gene expression. ORF57 interaction with RNA is necessary for …

Virus–host interplay between poly (ADP-ribose) polymerase 1 and oncogenic gammaherpesviruses

WC Chung, MJ Song - Frontiers in Microbiology, 2022 - frontiersin.org
The gammaherpesviruses, include the Epstein–Barr virus, Kaposi's sarcoma-associated
herpesvirus, and murine gammaherpesvirus 68. They establish latent infection in the B …

Upregulation of microRNA 711 mediates HIV-1 Vpr promotion of Kaposi's sarcoma-associated herpesvirus latency and induction of pro-proliferation and pro-survival …

Q Yan, R Zhao, C Shen, F Wang, W Li, SJ Gao… - Journal of …, 2018 - Am Soc Microbiol
Coinfection with HIV-1 and Kaposi's sarcoma-associated herpesvirus (KSHV) often leads to
AIDS-related malignancies, including Kaposi's sarcoma (KS) and primary effusion …

[HTML][HTML] KSHV LANA upregulates the expression of epidermal growth factor like domain 7 to promote angiogenesis

S Thakker, RC Strahan, AN Scurry, T Uppal… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Kaposi's sarcoma (KS) is a highly-vascularized tumor characterized by inflammation and
extensive neo-angiogenesis. The KS tumor microenvironment is rich in inflammatory and …

Activation and counteraction of antiviral innate immunity by KSHV: an Update

X Wei, K Lan - Science bulletin, 2018 - Elsevier
The innate immune responses triggering production of type I interferons and inflammatory
cytokines constitute a nonspecific innate resistance that eliminates invading pathogens …

Kaposi's sarcoma-associated herpesvirus-encoded LANA recruits topoisomerase IIβ for latent DNA replication of the terminal repeats

P Purushothaman, ME McDowell… - Journal of …, 2012 - Am Soc Microbiol
The latency-associated nuclear antigen (LANA) encoded by Kaposi's sarcoma-associated
herpesvirus (KSHV) plays a major role in maintaining latency and is critical for the perpetual …

Kaposi's sarcoma-associated herpesvirus infection induces the expression of neuroendocrine genes in endothelial cells

M Valiya Veettil, G Krishna, A Roy, A Ghosh… - Journal of …, 2020 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically associated with
endothelial Kaposi's sarcoma (KS) in immunocompromised individuals. KS lesion cells …

Regulation of the metastasis suppressor Nm23-H1 by tumor viruses

S Banerjee, HC Jha, ES Robertson - Naunyn-Schmiedeberg's archives of …, 2015 - Springer
Metastasis is the most common cause of cancer mortality. To increase the survival of
patients, it is necessary to develop more effective methods for treating as well as preventing …