[HTML][HTML] SCLC: epidemiology, risk factors, genetic susceptibility, molecular pathology, screening, and early detection

Q Wang, ZH Gümüş, C Colarossi, L Memeo… - Journal of Thoracic …, 2023 - Elsevier
We review research regarding the epidemiology, risk factors, genetic susceptibility,
molecular pathology, and early detection of SCLC, a deadly tumor that accounts for 14% of …

Lung cancer detection from CT image using improved profuse clustering and deep learning instantaneously trained neural networks

PM Shakeel, MA Burhanuddin, MI Desa - Measurement, 2019 - Elsevier
Automatic lung disease detection is a critical challenging task for researchers because of the
noise signals getting included into creative signals amid the image capturing process which …

High-dose versus standard-dose twice-daily thoracic radiotherapy for patients with limited stage small-cell lung cancer: an open-label, randomised, phase 2 trial

BH Grønberg, KT Killingberg, Ø Fløtten… - The Lancet …, 2021 - thelancet.com
Background Concurrent chemoradiotherapy is standard treatment for limited stage small-cell
lung cancer (SCLC). Twice-daily thoracic radiotherapy of 45 Gy in 30 fractions is considered …

Impact of aliphatic acyl and aromatic thioamide substituents on the anticancer activity of Ru (ii)-p-cymene complexes with acylthiourea ligands—in vitro and in vivo …

S Swaminathan, J Haribabu, MKM Subarkhan… - Dalton …, 2021 - pubs.rsc.org
Six different acylthiourea ligands (L1–L6) and their corresponding Ru (II)-p-cymene
complexes (P1–P6) were designed to explore the structure–activity relationship of the …

Prognostic and therapeutic significance of circulating tumor cells in patients with lung cancer

M Yousefi, P Ghaffari, R Nosrati, S Dehghani… - Cellular Oncology, 2020 - Springer
Background Lung cancer is the second most common cancer and the main cause of cancer-
related mortality worldwide. In spite of various efforts that have been made to facilitate the …

Small cell lung cancer

GP Kalemkerian, W Akerley, P Bogner… - Journal of the National …, 2013 - jnccn.org
Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈ 15%) are
small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in Oncology for …

[HTML][HTML] Incidence and survival of neuroendocrine tumours in the Netherlands according to histological grade: experience of two decades of cancer registry

CM Korse, BG Taal, MLF van Velthuysen… - European journal of …, 2013 - Elsevier
PURPOSE: Epidemiological studies on neuroendocrine tumours (NETs) generally show a
major increase in incidence. To investigate this increase, epidemiological data from the …

Italian, multicenter, phase III, randomized study of cisplatin plus etoposide with or without bevacizumab as first-line treatment in extensive-disease small-cell lung …

M Tiseo, L Boni, F Ambrosio, A Camerini… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Considering promising results in phase II studies, a randomized phase III trial was
designed to assess the efficacy of adding bevacizumab to first-line cisplatin plus etoposide …

LncRNA HOXA11‐AS drives cisplatin resistance of human LUAD cells via modulating miR‐454‐3p/Stat3

X Zhao, X Li, L Zhou, J Ni, W Yan, R Ma, J Wu… - Cancer …, 2018 - Wiley Online Library
Over the past several years, long non‐coding RNAs (lncRNAs) have attracted more and
more attention due to their special functions. They are vital biomarkers in multiple diseases …

Evaluation of circulating tumor cells and serological cell death biomarkers in small cell lung cancer patients undergoing chemotherapy

JM Hou, A Greystoke, L Lancashire… - The American journal of …, 2009 - Elsevier
Serological cell death biomarkers and circulating tumor cells (CTCs) have potential uses as
tools for pharmacodynamic blood-based assays and their subsequent application to early …