Methods and non-immunogenic compositions for treating inflammatory disorders

JR Binder, JC Higgins, MD Leach… - US Patent …, 2018 - Google Patents
Methods for making non-immunogenic anti-inflammatory cytokine compositions, comprising
(a) obtaining a liquid comprising cytokine producing cells from a mammalian donor;(b) …

Breakdown of deterministic lateral displacement efficiency for non-dilute suspensions: A numerical study

R Vernekar, T Krüger - Medical engineering & physics, 2015 - Elsevier
We investigate the effect of particle volume fraction on the efficiency of deterministic lateral
displacement (DLD) devices. DLD is a popular passive sorting technique for microfluidic …

Exploitation of blood non-Newtonian properties for ultrasonic measurement of hematocrit

B Pialot, J Gachelin, J Provost, O Couture - Scientific Reports, 2021 - nature.com
New processing techniques for manipulating blood and its components at a microfluidic
scale are currently implemented. As for extracorporeal circulation, the in-line evaluation and …

High-throughput white blood cell (leukocyte) enrichment from whole blood using hydrodynamic and inertial forces

B Lombodorj, HC Tseng, HY Chang, YW Lu… - Micromachines, 2020 - mdpi.com
A microfluidic chip, which can separate and enrich leukocytes from whole blood, is
proposed. The chip has 10 switchback curve channels, which are connected by straight …

A passive two-way microfluidic device for low volume blood-plasma separation

L Spigarelli, V Bertana, D Marchisio, L Scaltrito… - Microelectronic …, 2019 - Elsevier
Blood-plasma separation is one of the main concerns for Point-of-Care devices seeking to
retain cells of interest or analyze plasma biomarkers. The present work describes a novel …

Microfluidic techniques for platelet separation and enrichment

V Laxmi, S Tripathi, SS Joshi, A Agrawal - Journal of the Indian Institute of …, 2018 - Springer
One of the major areas of active research in microfluidics is in biological applications. These
applications often require complex analysis of biological fluids for clinical diagnostics. One …

Exponential magnetophoretic gradient for the direct isolation of basophils from whole blood in a microfluidic system

N Castaño, S Kim, AM Martin, SJ Galli, KC Nadeau… - Lab on a Chip, 2022 - pubs.rsc.org
Despite their rarity in peripheral blood, basophils play important roles in allergic disorders
and other diseases including sepsis and COVID-19. Existing basophil isolation methods …

Controlled incremental filtration: a simplified approach to design and fabrication of high-throughput microfluidic devices for selective enrichment of particles

SC Gifford, AM Spillane, SM Vignes, SS Shevkoplyas - Lab on a chip, 2014 - pubs.rsc.org
The number of microfluidic strategies aimed at separating particles or cells of a specific size
within a continuous flow system continues to grow. The wide array of biomedical and other …

Transient electrohydrodynamics of compound drops

A Behjatian, A Esmaeeli - Acta Mechanica, 2015 - Springer
The transient electrohydrodynamics of a compound drop under a uniform electric field of
small strength is investigated. A closed form analytical solution is developed for creeping …

Current status of the development of blood-based point-of-care microdevices

V Laxmi, S Tripathi, A Agrawal - Mechanical Sciences: The Way Forward, 2021 - Springer
Blood is one of the most common human tissues required to assess the human health
condition. In a conventional setup, disease diagnosis includes consultation with a health …