Combinatorial transcriptomic and genetic dissection of insulin/IGF‐1 signaling‐regulated longevity in Caenorhabditis elegans
Classical genetic analysis is invaluable for understanding the genetic interactions
underlying specific phenotypes, but requires laborious and subjective experiments to …
underlying specific phenotypes, but requires laborious and subjective experiments to …
Loci on chromosome 20 interact with rs16969968 to influence cigarettes per day in European ancestry individuals
Background The understanding of the molecular genetic contributions to smoking is largely
limited to the additive effects of individual single nucleotide polymorphisms (SNPs), but the …
limited to the additive effects of individual single nucleotide polymorphisms (SNPs), but the …
[HTML][HTML] Overcoming the “feast or famine” effect: improved interaction testing in genome-wide association studies
H Zhou, MS McPeek - bioRxiv, 2024 - ncbi.nlm.nih.gov
In genetic association analysis of complex traits, detection of interaction (either GxG or GxE)
can help to elucidate the genetic architecture and biological mechanisms underlying the …
can help to elucidate the genetic architecture and biological mechanisms underlying the …
Gene Interactions in Survival Data Analysis: A Data-Driven Approach Using Restricted Mean Survival Time and Literature Mining
Unveiling gene interactions is crucial for comprehending biological processes, particularly
their combined impact on phenotypes. Computational methodologies for gene interaction …
their combined impact on phenotypes. Computational methodologies for gene interaction …