Drugs are absorbed after oral administration as a consequence of a complex array of
interactions between the drug, its formulation, and the gastrointestinal (GI) tract. The …

In April 1986 a discussion meeting entitled'Technical aspects of intraluminal pH-metry using
pH-electrodes in man'was held in Zurich, Switzerland. The meeting brought together …

The pH in the upper gastrointestinal tract of young, healthy men and women was measured
in the fasting state and after administration of a standard solid and liquid meal. Calibrated …

In situ pH was measured simultaneously with microelectrodes in the stomach, duodenal
bulb, midduodenum, duodenojejunal junction, and proximal jejunum. Fourteen healthy …

The aim of this study was to define better the motor phenomena associated with the slowing
of gastric emptying by a duodenal lipid infusion. Antral, pyloric and duodenal motility were …

Methods FD and controls underwent 48-hour recording of DAE using endoclip-secured
RpHM capsules in the distal duodenal bulb. Subjects were nil per os except for meals eaten …

Intraluminal pH monitoring in man should be performed with disposable multichannel
assemblies that allow recordings at multiple sites and prevent transmission of infection …

Oral administration of pH buffers can reduce the development of spontaneous and
experimental metastases in mice, and has been proposed in clinical trials. Effectiveness of …

Background Gastro‐oesophageal reflux disease (GERD) and gastric acid hypersecretion
respond well to suppression of gastric acid secretion. However, clinical management and …

The proximal duodenal mucosa secretes HCO 3− that serves to protect the epithelium from
injury. In isolated human duodenal enterocytes in vitro, multiple luminal membrane proteins …