[HTML][HTML] Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification
The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …
Antibiotics: Pharmacokinetics, toxicity, resistance and multidrug efflux pumps
Ç Yılmaz, G Özcengiz - Biochemical pharmacology, 2017 - Elsevier
The discovery of penicillin followed by streptomycin, tetracycline, cephalosporins and other
natural, semi-synthetic and synthetic antimicrobials completely revolutionized medicine by …
natural, semi-synthetic and synthetic antimicrobials completely revolutionized medicine by …
Role of medicinal plants from North Western Himalayas as an efflux pump inhibitor against MDR AcrAB-TolC Salmonella enterica serovar typhimurium: In vitro and In …
J Mehta, R Rolta, K Dev - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Zingiber officinale Roscoe has been utilized
traditionally to cure various diseases like cold, cough, diarrhoea, nausea, asthma, vomiting …
traditionally to cure various diseases like cold, cough, diarrhoea, nausea, asthma, vomiting …
[HTML][HTML] Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development
For millennia, humanity has relied on plants for its medicines, and modern pharmacology
continues to reexamine and mine plant metabolites for novel compounds and to guide …
continues to reexamine and mine plant metabolites for novel compounds and to guide …
[HTML][HTML] The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy
Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
RND efflux pump mediated antibiotic resistance in Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa: a major issue worldwide
Therapeutic failures against diseases due to resistant Gram-negative bacteria have become
a major threat nowadays as confirmed by surveillance reports across the world. One of the …
a major threat nowadays as confirmed by surveillance reports across the world. One of the …
[PDF][PDF] Antimicrobial compounds of plant origin as efflux pump inhibitors: new avenues for controlling multidrug resistant pathogens
The emergence of multiple drug resistant pathogenic bacteria has severely constricted the
antimicrobial options of treating infectious diseases. One of the powerful mechanisms of …
antimicrobial options of treating infectious diseases. One of the powerful mechanisms of …
Effect of piperine on the inhibitory potential of MexAB-OprM efflux pump and imipenem resistance in carbapenem-resistant Pseudomonas aeruginosa
Y Liu, R Zhu, X Liu, D Li, M Guo, B Fei, Y Ren… - Microbial …, 2023 - Elsevier
The escalating prevalence of carbapenem-resistant Pseudomonas aeruginosa (CRPA)
poses a significant threat to global public health through the spread of its 'high-risk'clones …
poses a significant threat to global public health through the spread of its 'high-risk'clones …
Do phenothiazines possess antimicrobial and efflux inhibitory properties?
EM Grimsey, LJV Piddock - FEMS Microbiology Reviews, 2019 - academic.oup.com
Antibiotic resistance is a global health concern; the rise of drug-resistant bacterial infections
is compromising the medical advances that resulted from the introduction of antibiotics at the …
is compromising the medical advances that resulted from the introduction of antibiotics at the …
Non-antibiotic antimicrobial interventions and antimicrobial stewardship in wound care
R Cooper, K Kirketerp-Møller - Journal of wound care, 2018 - magonlinelibrary.com
Control of wound infection today relies largely on antibiotics, but the continual emergence of
antibiotic-resistant microorganisms threatens a return to the pre-antibiotic era when …
antibiotic-resistant microorganisms threatens a return to the pre-antibiotic era when …