Inflammation is an essential component of several respiratory diseases, such as chronic
obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome …

Acute respiratory distress syndrome (ARDS) can be induced by multiple clinical factors,
including sepsis, acute pancreatitis, trauma, intestinal ischemia/reperfusion and burns …

Importance Epigenetic clocks represent molecular evidence of disease risk and aging
processes and have been used to identify how social and lifestyle characteristics are …

Background Obesity is a multifactorial and chronic condition of growing universal concern. It
has recently been reported that bariatric surgery is a more successful treatment for severe …

Epigenetic mechanisms such as aberrant DNA methylation (DNAme) are known to drive
esophageal squamous cell carcinoma (ESCC), yet they remain poorly understood. Here, we …

Background Sepsis is a highly heterogeneous syndrome with diverse immune status and
varied bioprocesses among individuals. The heterogeneity of sepsis could be associated …

Colon adenocarcinoma (COAD) is one of the most prevalent malignant tumors worldwide.
Immune genes (IGs) have a considerable correlation with tumor initiation and prognosis …

Background and objective Alzheimer's disease (AD) is the most common type of dementia,
with its pathology like beta-amyloid and phosphorylated tau beginning several years before …

Revealing the key genes involved in polycystic ovary syndrome (PCOS) and elucidating its
pathogenic mechanism is of extreme importance for the development of targeted clinical …

Ethnopharmacological relevance Loganin, an iridoid glycoside, is one of the quality control
indexes of Cornus officinalis Sieb. et Zucc. Increasing evidence emphasize the important …