The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Introduction: Spontaneous non-traumatic intracerebral hemorrhage (ICH) is most often
caused by small vessel diseases: deep perforator arteriopathy (hypertensive arteriopathy) or …

Inflammation that contributes to acute cerebrovascular disease is driven by the
proinflammatory cytokine interleukin-1 and is known to exacerbate resulting injury. The …

Cells of myeloid origin, such as microglia and macrophages, act at the crossroads of several
inflammatory mechanisms during pathophysiology. Besides pro-inflammatory activity (M1 …

The inflammation theory of depression, proposed over 20 years ago, was influenced by
early studies on T cell responses and since then has been a stimulus for numerous research …

Microglial activation is considered as the critical pathogenic event in diverse central nervous
system disorders including cerebral ischemia. Proinflammatory responses of activated …

Stroke is the world's leading cause of disability with limited brain repair treatments which
effectively improve long‐term neurological deficits. The neuroinflammatory responses …

Much evidence demonstrated that autophagy played an important role in neural
inflammation response after ischemia stroke. However, the specific effect of microglia …

Inflammation within the brain or spinal cord has the capacity to damage neurons and is
known to contribute to long-term disability in a spectrum of central nervous system (CNS) …

Low-grade inflammation and endothelial dysfunction are related to cognitive decline and
dementia, in a complex interplay with vascular factors and aging. We investigated, in an …