Navigating the pitfalls of applying machine learning in genomics

S Whalen, J Schreiber, WS Noble… - Nature Reviews Genetics, 2022 - nature.com
The scale of genetic, epigenomic, transcriptomic, cheminformatic and proteomic data
available today, coupled with easy-to-use machine learning (ML) toolkits, has propelled the …

Applications of artificial intelligence in forensic sciences: C urrent potential benefits, limitations and perspectives

N Galante, R Cotroneo, D Furci, G Lodetti… - International journal of …, 2023 - Springer
In recent years, new studies based on artificial intelligence (AI) have been conducted in the
forensic field, posing new challenges and demonstrating the advantages and disadvantages …

Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging

A Li, Z Koch, T Ideker - Journal of internal medicine, 2022 - Wiley Online Library
Numerous studies have shown that epigenetic age—an individual's degree of aging based
on patterns of DNA methylation—can be computed and is associated with an array of factors …

DNA methylation of the ELOVL2, FHL2, KLF14, C1orf132/MIR29B2C, and TRIM59 genes for age prediction from blood, saliva, and buccal swab samples

SE Jung, SM Lim, SR Hong, EH Lee, KJ Shin… - Forensic Science …, 2019 - Elsevier
Many studies have reported age-associated DNA methylation changes and age-predictive
models in various tissues and body fluids. Although age-associated DNA methylation …

Massively parallel sequencing techniques for forensics: A review

B Bruijns, R Tiggelaar, H Gardeniers - Electrophoresis, 2018 - Wiley Online Library
DNA sequencing, starting with Sanger's chain termination method in 1977 and evolving into
the next generation sequencing (NGS) techniques of today that employ massively parallel …

Meta-analyses of the n-back working memory task: fMRI evidence of age-related changes in prefrontal cortex involvement across the adult lifespan

ZA Yaple, WD Stevens, M Arsalidou - NeuroImage, 2019 - Elsevier
Working memory, a fundamental cognitive function that is highly dependent on the integrity
of the prefrontal cortex, is known to show age-related decline across the typical healthy adult …

Chemometrics in forensic science: approaches and applications

G Sauzier, W van Bronswijk, SW Lewis - Analyst, 2021 - pubs.rsc.org
Forensic investigations are often reliant on physical evidence to reconstruct events
surrounding a crime. However, there remains a need for more objective approaches to …

A survey on deep learning in DNA/RNA motif mining

Y He, Z Shen, Q Zhang, S Wang… - Briefings in …, 2021 - academic.oup.com
DNA/RNA motif mining is the foundation of gene function research. The DNA/RNA motif
mining plays an extremely important role in identifying the DNA-or RNA-protein binding site …

Recent progress, methods and perspectives in forensic epigenetics

A Vidaki, M Kayser - Forensic Science International: Genetics, 2018 - Elsevier
Forensic epigenetics, ie, investigating epigenetics variation to resolve forensically relevant
questions unanswerable with standard forensic DNA profiling has been gaining substantial …

[HTML][HTML] Recent advances in Forensic DNA Phenotyping of appearance, ancestry and age

M Kayser, W Branicki, W Parson, C Phillips - Forensic Science International …, 2023 - Elsevier
Abstract Forensic DNA Phenotyping (FDP) comprises the prediction of a person's externally
visible characteristics regarding appearance, biogeographic ancestry and age from DNA of …