Advances in the treatment of prolactinomas
MP Gillam, ME Molitch, G Lombardi… - Endocrine …, 2006 - academic.oup.com
Prolactinomas account for approximately 40% of all pituitary adenomas and are an
important cause of hypogonadism and infertility. The ultimate goal of therapy for …
important cause of hypogonadism and infertility. The ultimate goal of therapy for …
What can we learn from rodents about prolactin in humans?
N Ben-Jonathan, CR LaPensee… - Endocrine …, 2008 - academic.oup.com
Abstract Prolactin (PRL) is a 23-kDa protein hormone that binds to a single-span membrane
receptor, a member of the cytokine receptor superfamily, and exerts its action via several …
receptor, a member of the cytokine receptor superfamily, and exerts its action via several …
Prolactin and oxytocin: potential targets for migraine treatment
AK Szewczyk, S Ulutas, T Aktürk, L Al-Hassany… - The Journal of …, 2023 - Springer
Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully
understood. Besides the role of inflammatory mediators that interact with the …
understood. Besides the role of inflammatory mediators that interact with the …
Hyperprolactinemia and prolactinomas
T Mancini, FF Casanueva, A Giustina - Endocrinology and metabolism …, 2008 - Elsevier
Hyperprolactinemia is one of the most frequently diagnosed clinical disorders in routine
endocrine practice. Any process interfering with dopamine synthesis, its transport to the …
endocrine practice. Any process interfering with dopamine synthesis, its transport to the …
Molecular mechanisms of prolactin and its receptor
CL Brooks - Endocrine reviews, 2012 - academic.oup.com
Prolactin and the prolactin receptors are members of a family of hormone/receptor pairs
which include GH, erythropoietin, and other ligand/receptor pairs. The mechanisms of these …
which include GH, erythropoietin, and other ligand/receptor pairs. The mechanisms of these …
Medical treatment of prolactinomas
A Colao, S Savastano - Nature Reviews Endocrinology, 2011 - nature.com
Prolactinomas, the most prevalent type of neuroendocrine disease, account for
approximately 40% of all pituitary adenomas. The most important clinical problems …
approximately 40% of all pituitary adenomas. The most important clinical problems …
A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer
SS Tworoger, AH Eliassen, P Sluss… - Journal of Clinical …, 2007 - ascopubs.org
Purpose Epidemiologic studies suggest that prolactin is associated with breast cancer risk in
older women. Because of limited prospective data, particularly in younger women, we …
older women. Because of limited prospective data, particularly in younger women, we …
The RNA-binding protein Sam68 is a multifunctional player in human cancer
P Bielli, R Busà, MP Paronetto… - Endocrine-related …, 2011 - erc.bioscientifica.com
Resistance to chemotherapy is a major complication in the treatment of advanced breast
cancer. Estrogens and prolactin (PRL) are implicated in the pathogenesis of breast cancer …
cancer. Estrogens and prolactin (PRL) are implicated in the pathogenesis of breast cancer …
Prolactin: A hormone with diverse functions from mammary gland development to cancer metastasis
ÖK Atıcı, N Govindrajan, I Lopetegui-González… - Seminars in Cell & …, 2021 - Elsevier
Prolactin has a rich mechanistic set of actions and signaling in order to elicit developmental
effects in mammals. Historically, prolactin has been appreciated as an endocrine peptide …
effects in mammals. Historically, prolactin has been appreciated as an endocrine peptide …
Giant prolactinomas: the therapeutic approach
AB Moraes, C Marques dos Santos Silva… - Clinical …, 2013 - Wiley Online Library
Background Giant prolactinomas are an unusual subset of macroprolactinomas and are
more commonly found in men. The goal of this review is to propose a giant prolactinoma …
more commonly found in men. The goal of this review is to propose a giant prolactinoma …