Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Alcohol use disorder (AUD) has been associated with neurodegenerative diseases such as
Alzheimer's and Parkinson's disease. Prolonged excessive alcohol intake contributes to …

Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD)
and amyotrophic lateral sclerosis (ALS), increase as the population ages around the world …

Identification of causal variants and genes underlying genome-wide association study
(GWAS) loci is essential to understand the biology of alcohol use disorder (AUD) and drinks …

Epidemiological studies suggest that heavy alcohol use early in life is associated with
increased risk for Alzheimer's disease (AD). However, mechanisms connecting AD with …

Alzheimer's disease (AD) is a neurodegenerative disease that impacts 45 million people
worldwide and is ranked as the 6th top cause of death among all adults by the Centers for …

Cigarette smoking and alcohol use are among the most prevalent substances used
worldwide and account for a substantial proportion of preventable morbidity and mortality …

Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …

Alzheimer's Disease and related dementias (ADRD) are an increasing threat to global
health initiatives. Efforts to prevent the development of ADRD require understanding …

Binge drinking is rising among aged adults (> 65 years of age), however the contribution of
alcohol misuse to neurodegenerative disease development is not well understood. Both …