Oxygen is an essential element for life and without oxygen humans can survive for few
minutes only. There should be a balance between oxygen demand and delivery in order to …

Chronic obstructive pulmonary disease (COPD) involves a complex interaction of structural
and functional abnormalities. The two have long been studied in isolation. However …

Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Background Hyperpolarized noble gas MRI helps measure lung ventilation, but clinical
translation remains limited. Free-breathing proton MRI may help quantify lung function using …

Purpose To directly compare magnetic resonance (MR) imaging and computed tomography
(CT) parametric response map (PRM) measurements of gas trapping and emphysema in ex …

Positron emission tomography (PET) provides three-dimensional images of the distributions
of radionuclides that have been inhaled or injected into the lungs. By using radionuclides …

Growth of solid tumors beyond a certain mass is dependent on the vascular bed from pre-
existing host vasculature. The process of angiogenesis is essential not only for primary …

Background Advanced heterogeneous emphysema with hyperinflation impacts exercise
tolerance in COPD. Bronchoscopic lung volume reduction using Zephyr endobronchial …

Although it is known that structural and functional changes in the pulmonary vasculature and
parenchyma occur in the progress of chronic obstructive pulmonary disease (COPD) …

PURPOSE: To assess the relationship between lung parenchymal destruction and impaired
pulmonary perfusion on a lobar level using CT and MRI in patients with emphysema …