Chitosan-based scaffolds as drug delivery systems in bone tissue engineering

R Bharathi, SS Ganesh, G Harini, K Vatsala… - International Journal of …, 2022 - Elsevier
The bone tissue engineering approach for treating large bone defects becomes necessary
when the tissue damage surpasses the threshold of the inherent regenerative ability of the …

[HTML][HTML] Emerging early diagnostic methods for acute kidney injury

Z Xiao, Q Huang, Y Yang, M Liu, Q Chen, J Huang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Many factors such as trauma and COVID-19 cause acute kidney injury (AKI). Late AKI have
a very high incidence and mortality rate. Early diagnosis of AKI provides a critical therapeutic …

Extremely strong and tough chitosan films mediated by unique hydrated chitosan crystal structures

Q Zhang, Y Chen, P Wei, Y Zhong, C Chen, J Cai - Materials Today, 2021 - Elsevier
Chitosan-based materials have attracted considerable attention owing to their inherent
biodegradability, biocompatibility, and antimicrobial properties. However, the establishment …

[HTML][HTML] Passively-targeted mitochondrial tungsten-based nanodots for efficient acute kidney injury treatment

Q Huang, Y Yang, T Zhao, Q Chen, M Liu, S Ji, Y Zhu… - Bioactive materials, 2023 - Elsevier
Acute kidney injury (AKI) can lead to loss of kidney function and a substantial increase in
mortality. The burst of reactive oxygen species (ROS) plays a key role in the pathological …

Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer

F Jin, J Qi, D Liu, Y You, G Shu, Y Du, J Wang… - Journal of Controlled …, 2021 - Elsevier
Photodynamic therapy (PDT) and chemotherapy show clinical promise in destroying
orthotopic tumors but are insufficient against abscopal metastases. The research reports the …

[HTML][HTML] Double-network hydrogel enhanced by SS31-loaded mesoporous polydopamine nanoparticles: Symphonic collaboration of near-infrared photothermal …

QS Deng, Y Gao, BY Rui, XR Li, PL Liu, ZY Han… - Bioactive materials, 2023 - Elsevier
Diabetic wound healing has become a serious healthcare challenge. The high-glucose
environment leads to persistent bacterial infection and mitochondrial dysfunction, resulting …

Reversing Acute Kidney Injury through Coordinated Interplay of Anti‐Inflammation and Iron Supplementation

R Duan, Y Li, R Zhang, X Hu, Y Wang… - Advanced …, 2023 - Wiley Online Library
Acute kidney injury (AKI) induced by ischemia reperfusion is closely related to mitochondrial
dysfunction. Nicotinamide adenine dinucleotide (NAD+) can enhance the mitochondrial …

1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic Acid Acetoxymethyl Ester Loaded Reactive Oxygen Species Responsive Hyaluronic Acid–Bilirubin …

Y Wang, M Pu, J Yan, J Zhang, H Wei, L Yu, X Yan… - ACS …, 2022 - ACS Publications
Calcium overload is one of the early determinants of the core cellular events that contribute
to the pathogenesis of acute kidney injury (AKI), which include oxidative stress, ATP …

Sequential therapy of acute kidney injury with a DNA nanodevice

Q Chen, F Ding, S Zhang, Q Li, X Liu, H Song… - Nano Letters, 2021 - ACS Publications
The high demand for acute kidney injury (AKI) therapy calls the development of
multifunctional nanomedicine for renal management with programmable pharmacokinetics …

[HTML][HTML] Construction of a lactate-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in kidney renal clear cell …

Z Sun, W Tao, X Guo, C Jing, M Zhang… - Frontiers in …, 2022 - frontiersin.org
Kidney renal clear cell carcinoma (KIRC) is one of the most prevalent primary malignancies
with high heterogeneity in the urological system. Growing evidence implies that lactate is a …