Most clinically significant antibiotic resistance is determined by genes located on
extrachromosomal DNA elements called plasmids (31, 108, 154). Different species of …

Vancomycin is a unique glycopeptide structurally unrelated to any currently available
antibiotic. It also has a unique mode of action inhibiting the second stage of cell wall …

The lack of a standardized, statistically reliable method for in vitro determinations of the
minimal lethal or bactericidal concentrations of antibiotics has complicated analyses of …

One of the unique features of p-lactam antibiotics and other cell-wall inhibitors like
vancomycin and bacitracin is that they can rapidly kill and in many cases lyse susceptible …

Kucers' The Use of Antibiotics is the definitive, internationally-authored reference, providing
everything that the infectious diseases specialist and prescriber needs to know about …

Concentrations of vancomycin in bones of 14 patients undergoing total hip arthroplasty
(group 1) and 5 patients with osteomyelitis (group 2) were studied. Group 1 received …

Staphylococcus aweus is still an important hospital pathogen and it is the most frequently
isolated single bacterial species from infected wounds especially from patients who have …

INTRODUCTION Antibiotic research isone of the most exciting fields in chemotherapy (237,
238). As physicians and users of antibiotics, we demand that antibiotics be active against …

Vancomycin inhibits the second stage of cell wall synthesis in susceptible bacteria.
Furthermore, there is evidence that vancomycin also alters the permeability of the cell …

Tobramycin for Methicillin-Susceptible and Methicillin- Page 1 ANTIMICROBIAL AGENTS AND
CHEMOTHERAPY, Nov. 1982, p. 903-905 Vol. 22, No. 5 0066-4804/82/110903-03$02.00/0 …