Isobolographic analysis of interaction between nisoxetine‐and mepivacaine‐induced spinal blockades in rats

YM Leung, CC Chu, CS Kuo, YW Chen… - Fundamental & …, 2014 - Wiley Online Library
Although nisoxetine has been shown to elicit cutaneous (peripheral) anesthesia, spinal
(central) anesthesia with nisoxetine was not exposed. The aim of this study was to examine …

Cutaneous analgesia and systemic toxicity of carbetapentane and caramiphen in rats

CH Hung, CC Chu, YC Chen, KS Liu… - Regional Anesthesia & …, 2012 - rapm.bmj.com
Background Caramiphen produces spinal anesthesia; caramiphen and carbetapentane
have never been tested as infiltrative cutaneous analgesic. The aim of this study was to …

Spinal anesthesia with diphenhydramine and pheniramine in rats

CH Hung, CC Chu, YC Chen, YW Chen, ZY Li… - European journal of …, 2011 - Elsevier
The aim of this study was to evaluate the local anesthetic effects of pheniramine and
diphenhydramine, two histamine H1 receptor antagonists, on spinal anesthesia and their …

Intrathecal propranolol displays long-acting spinal anesthesia with a more sensory-selective action over motor blockade in rats

YW Chen, CC Chu, YC Chen, CH Hung… - European journal of …, 2011 - Elsevier
To prevent cardiovascular effects of peripherally administered propranolol, the aim of this
study was to evaluate the spinal anesthetic effect of propranolol, a Na±channel blocker. After …

Nisoxetine blocks sodium currents and elicits spinal anesthesia in rats

YM Leung, CC Chu, CS Kuo, YW Chen… - Pharmacological …, 2013 - Springer
Background Although nisoxetine has been shown to elicit infiltrative cutaneous local
anesthesia, the inhibition of voltage-gated Na+ channels by nisoxetine has not been …

Isoflurane for spinal anesthesia in the rat

CH Hung, CC Chu, YC Chen, YW Chen, HJ Hong… - Neuroscience …, 2011 - Elsevier
Although isoflurane, a non-water soluble agent, has been known to block Na+ currents, its
spinal anesthetic effect was not exposed. The aim of this experiment was to evaluate the …

Clonidine as adjuvant for oxybuprocaine, bupivacaine or dextrorphan has a significant peripheral action in intensifying and prolonging analgesia in response to local …

YW Chen, CC Chu, YC Chen, CH Hung, MI Hsueh… - Neuroscience …, 2011 - Elsevier
The aim of the study was to evaluate co-administration of clonidine with oxybuprocaine
(ester type), bupivacaine (amide type) or dextrorphan (non-ester or non-amide type) and to …

Antibacterial activity chemical composition relationship of the essential oils from cultivated plants from Serbia

NS Stanković, LR Čomić, BD Kocić, DM Nikolić… - Hemijska …, 2011 - doiserbia.nb.rs
U radu su prikazani rezultati proučavanja hemijskog sastava i antibakterijske aktivnosti
etarskih ulja gajenih biljnih vrsta Thymus vulgaris L.(timus) i Lavandula angustifolia …

Lidocaine for prolonged and intensified spinal anesthesia by coadministration of propranolol in the rat

YW Chen, CC Chu, YC Chen, CH Hung, YT Li… - Neuroscience …, 2011 - Elsevier
Although the coadministration of lidocaine with propranolol interferes with the metabolic
profile (pharmacokinetics), its pharmacodynamics is still unclear. In this report, we …

The use of carbetapentane for spinal anesthesia and use-dependent block of sodium currents

YM Leung, JI Tzeng, CS Kuo, YW Chen, CC Chu… - European journal of …, 2013 - Elsevier
Although carbetapentane produces skin (peripheral) infiltrative analgesia, the underlying
mechanism of carbetapentane in local anesthesia is not well understood. The purpose of the …