[HTML][HTML] Targeting non-coding RNAs to overcome cancer therapy resistance

BQ Chen, MP Dragomir, C Yang, Q Li, D Horst… - Signal transduction and …, 2022 - nature.com
It is now well known that non-coding RNAs (ncRNAs), rather than protein-coding transcripts,
are the preponderant RNA transcripts. NcRNAs, particularly microRNAs (miRNAs), long non …

Bcl-2 antiapoptotic family proteins and chemoresistance in cancer

S Maji, S Panda, SK Samal, O Shriwas, R Rath… - Advances in cancer …, 2018 - Elsevier
Cancer is a daunting global problem confronting the world's population. The most frequent
therapeutic approaches include surgery, chemotherapy, radiotherapy, and more recently …

[HTML][HTML] A six-microRNA panel in plasma was identified as a potential biomarker for lung adenocarcinoma diagnosis

X Zhou, W Wen, X Shan, W Zhu, J Xu, R Guo… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Differently expressed microRNAs (miRNAs) in the plasma of lung adenocarcinoma (LA)
patients might serve as biomarkers for LA detection. MiRNA expression profiling was …

[HTML][HTML] Circulating cell-free microRNAs as clinical cancer biomarkers

V Armand-Labit, A Pradines - Biomolecular concepts, 2017 - degruyter.com
MicroRNAs (miRNAs) are non-coding small RNAs that are master regulators of genic
expression and consequently of many cellular processes. But their expression is often …

[HTML][HTML] The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications

H Zheng, Y Zhan, S Liu, J Lu, J Luo, J Feng… - Journal of Experimental & …, 2018 - Springer
Non-small cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer cases,
and it is one of the leading causes of cancer death in both men and women worldwide due …

[HTML][HTML] Epigenetics in non-small cell lung cancer: from basics to therapeutics

J Ansari, RE Shackelford, H El-Osta - Translational lung cancer …, 2016 - ncbi.nlm.nih.gov
Lung cancer remains the number one cause of cancer-related deaths worldwide with
221,200 estimated new cases and 158,040 estimated deaths in 2015. Approximately 80% of …

[HTML][HTML] Integrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer

M Sun, H Song, S Wang, C Zhang, L Zheng… - Journal of hematology & …, 2017 - Springer
Background With persistent inconsistencies in colorectal cancer (CRC) miRNAs expression
data, it is crucial to shift toward inclusion of a “pre-laboratory” integrated analysis to expedite …

Essential functions of miR‐125b in cancer

B Peng, PY Theng, MTN Le - Cell proliferation, 2021 - Wiley Online Library
MicroRNAs (miRNAs) are small and highly conserved non‐coding RNAs that silence target
mRNAs, and compelling evidence suggests that they play an essential role in the …

[HTML][HTML] miRNAs as biomarkers and therapeutic targets in non-small cell lung cancer: current perspectives

M Florczuk, A Szpechcinski… - Targeted oncology, 2017 - Springer
Lung cancer is the most common cancer worldwide. Up to 85% of lung cancer cases are
diagnosed as non-small cell lung cancer (NSCLC). The effectiveness of NSCLC treatment is …

MicroRNAs as a drug resistance mechanism to targeted therapies in EGFR-mutated NSCLC: Current implications and future directions

A Leonetti, YG Assaraf, PD Veltsista… - Drug Resistance …, 2019 - Elsevier
The introduction of EGFR-tyrosine kinase inhibitors (TKIs) has revolutionized the treatment
and prognosis of non-small cell lung cancer (NSCLC) patients harboring epidermal growth …