Rehabilitation: neurogenic bone loss after spinal cord injury

GE Leone, DC Shields, A Haque, NL Banik - Biomedicines, 2023 - mdpi.com
Osteoporosis is a common skeletal disorder which can severely limit one's ability to
complete daily tasks due to the increased risk of bone fractures, reducing quality of life …

Regulation of bone by mechanical loading, sex hormones, and nerves: Integration of such regulatory complexity and implications for bone loss during space flight and …

DA Hart - Biomolecules, 2023 - mdpi.com
During evolution, the development of bone was critical for many species to thrive and
function in the boundary conditions of Earth. Furthermore, bone also became a storehouse …

Electrical stimulation exercise for people with spinal cord injury: A healthcare provider perspective

DR Dolbow, AS Gorgey, TE Johnston… - Journal of Clinical …, 2023 - mdpi.com
Electrical stimulation exercise has become an important modality to help improve the
mobility and health of individuals with spinal cord injury (SCI). Electrical stimulation is used …

Clemastine in remyelination and protection of neurons and skeletal muscle after spinal cord injury

A Myatich, A Haque, C Sole… - Neural Regeneration …, 2023 - journals.lww.com
Spinal cord injuries affect nearly five to ten individuals per million every year. Spinal cord
injury causes damage to the nerves, muscles, and the tissue surrounding the spinal cord …

Role of stem cell-derived exosomes and microRNAs in spinal cord injury

J Hwang, S Jang, C Kim, S Lee, HS Jeong - International Journal of …, 2023 - mdpi.com
Neurological disorders represent a global health problem. Current pharmacological
treatments often lead to short-term symptomatic relief but have dose-dependent side effects …

Mechanism of skeletal muscle atrophy after spinal cord injury: A narrative review

X Xu, Z Talifu, CJ Zhang, F Gao, H Ke, YZ Pan… - Frontiers in …, 2023 - frontiersin.org
Spinal cord injury leads to loss of innervation of skeletal muscle, decreased motor function,
and significantly reduced load on skeletal muscle, resulting in atrophy. Factors such as …

DC electrical stimulation enhances proliferation and differentiation on N2a and MC3T3 cell lines

D Martín, J Bocio-Nuñez, SF Scagliusi, P Pérez… - Journal of Biological …, 2022 - Springer
Background Electrical stimulation is a novel tool to promote the differentiation and
proliferation of precursor cells. In this work we have studied the effects of direct current (DC) …

DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A2 mediated lysosomal membrane permeabilization after spinal cord injury

Y Chen, H Zhang, L Jiang, W Cai… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Autophagy is a protective factor for controlling neuronal
damage, while necroptosis promotes neuroinflammation after spinal cord injury (SCI) …

[HTML][HTML] The Role of Oxidative Stress in Multiple Exercise-Regulated Bone Homeostasis

H Gao, Y Zhao, L Zhao, Z Wang, K Yan, B Gao… - Aging and …, 2023 - ncbi.nlm.nih.gov
Bone is a tissue that is active throughout the lifespan, and its physiological activities, such as
growth, development, absorption, and formation, are always ongoing. All types of stimulation …

Analysis of zinc and stromal immunity in disuse osteoporosis: Mendelian randomization and transcriptomic analysis

F Lyu, L Wang, Y Jia, Y Wang, H Qi, Z Dai… - Orthopaedic …, 2023 - Wiley Online Library
Objective Disuse osteoporosis is known to be primarily caused by a lack of exercise.
However, the causal relationships between zinc and immunity and disuse osteoporosis …