Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

Innate immunity represents the semi-specific first line of defense and provides the initial host
response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive …

Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 in Saudi
Arabia and has caused over 2400 cases and more than 800 deaths. Epidemiological …

The excellent clinical efficacy of anti-interleukin 17A (IL-17A) biologics on psoriasis indicates
a crucial pathogenic role of IL-17A in this autoinflammatory skin disease. IL-17A accelerates …

Abstract Micro-/nanoplastics (MNPLs), novel environmental pollutants, widely exist in the
environment and life and bring health risks. Previous studies have shown that NMPLs can …

Although the pathogenic mechanisms underlying axial spondyloarthritis (axSpA) and
psoriatic arthritis (PsA) are not fully elucidated, several lines of evidence suggest that …

Fungal infections include a wide range of opportunistic and invasive diseases. Two of four
major fatal diseases in patients with human immunodeficiency virus (HIV) infection are …

Research in the pathogenesis of inflammatory skin diseases, such as skin dermatitis and
psoriasis, has experienced some relevant breakthroughs in recent years. The understanding …

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease that is defined by
loss of upper and lower motor neurons, associated with accumulation of protein aggregates …

Psoriasis is a multifactorial recalcitrant inflammatory skin disease characterized by
bothersome scaly reddish plaques especially on frequently chafed body parts, such as the …