Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells

B Jia, L Madsen, RK Petersen, N Techer, R Kopperud… - PloS one, 2012 - journals.plos.org
Human mesenchymal stem cells are primary multipotent cells capable of differentiating into
several cell types including adipocytes when cultured under defined in vitro conditions. In …

The importance of dietary modulation of cAMP and insulin signaling in adipose tissue and the development of obesity

L Madsen, K Kristiansen - Annals of the New York Academy of …, 2010 - Wiley Online Library
Adipose tissue plays a pivotal role in whole body energy homeostasis. In this review, we
summarize knowledge of the seemingly paradoxical roles of insulin and cyclic adenosine …

High-glycemic index carbohydrates abrogate the antiobesity effect of fish oil in mice

Q Hao, HH Lillefosse, E Fjære… - American Journal …, 2012 - journals.physiology.org
Fish oil rich in n-3 polyunsaturated fatty acids is known to attenuate diet-induced obesity and
adipose tissue inflammation in rodents. Here we aimed to investigate whether different …

Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J mice

E Fjære, UL Aune, K Røen, AH Keenan, T Ma… - Journal of Biological …, 2014 - ASBMB
Chronic low grade inflammation is closely linked to obesity-associated insulin resistance. To
examine how administration of the anti-inflammatory compound indomethacin, a general …

A safflower oil based high‐fat/high‐sucrose diet modulates the gut microbiota and liver phospholipid profiles associated with early glucose intolerance in the absence …

NB Danneskiold‐Samsøe, D Andersen… - Molecular Nutrition & …, 2017 - Wiley Online Library
Scope Omega‐6 (n‐6) PUFA‐rich diets are generally considered obesogenic in rodents.
Here, we examined how long‐term intake of a high‐fat/high‐sucrose (HF/HS) diet based on …

Dietary proteins, brown fat, and adiposity

L Madsen, LS Myrmel, E Fjære, J Øyen… - Frontiers in …, 2018 - frontiersin.org
High protein diets have become popular for body weight maintenance and weight loss
despite controversies regarding efficacy and safety. Although both weight gain and weight …

Maternal plasma polyunsaturated fatty acid levels during pregnancy and childhood lipid and insulin levels

AJ Vidakovic, VWV Jaddoe, T Voortman… - Nutrition, Metabolism …, 2017 - Elsevier
Background and aims Maternal polyunsaturated fatty acid (PUFA) levels are associated with
cord blood lipid and insulin levels. Not much is known about the influence of maternal …

Insulin induces fatty acid desaturase expression in human monocytes

I Arbo, C Halle, D Malik, HR Brattbakk… - … journal of clinical and …, 2011 - Taylor & Francis
Increasing evidence suggests that fatty acid desaturases, rate-limiting enzymes in
unsaturated fatty acid biosynthesis, are important factors in the pathogenesis of lipid …

[HTML][HTML] Effects of exercise and dietary protein sources on adiposity and insulin sensitivity in obese mice

E Fjære, LS Myrmel, DO Lützhøft, H Andersen… - The Journal of nutritional …, 2019 - Elsevier
Low-fat diets and exercise are generally assumed to ameliorate obesity-related metabolic
dysfunctions, but the importance of exercise vs. dietary changes is debated. Male C57BL/6J …

Fish intake, erythrocyte n-3 fatty acid status and metabolic health in Danish adolescent girls and boys

L Lauritzen, LBS Harsløf, LI Hellgren… - British journal of …, 2012 - cambridge.org
Marine n-3 long-chain PUFA (n-3 LCPUFA) may have a beneficial effect on several aspects
of the metabolic syndrome (dyslipidaemia, insulin resistance, hypertension and abdominal …