Persistent low-grade inflammation and premature ageing are hallmarks of the uremic
phenotype and contribute to impaired health status, reduced quality of life, and premature …

Chronic kidney disease (CKD) is a complex and multifactorial disease, and one of the most
prevalent worldwide. Chronic kidney disease–mineral bone disorders (CKD–MBD) with …

Irisin protects the cardiovascular system against vascular diseases. However, its role in
chronic kidney disease (CKD)-associated vascular calcification (VC) and the underlying …

Chronic kidney disease is highly prevalent worldwide. The decline of renal function is
associated with inadequate removal of a variety of uremic toxins that exert detrimental …

Ferroptosis is a recently recognized form of nonapoptotic cell death that is triggered by
reactive oxidative species (ROS) due to iron overload, lipid peroxidation accumulation, or …

Vascular calcification (VC) is one of the major causes of cardiovascular morbidity and
mortality in patients with chronic kidney disease (CKD). VC is a complex process expressing …

Oxidative stress and apoptosis of vascular smooth muscle cells (VSMCs) are key to vascular
calcification in patients with chronic kidney disease (CKD). The mitochondria-targeted …

Vascular calcification (VC), which is closely associated with significant mortality in
cardiovascular disease, chronic kidney disease (CKD), and/or diabetes mellitus, is …

Vascular calcification (VC) is associated with aging, cardiovascular and renal diseases and
results in poor morbidity and increased mortality. VC occurs in patients with chronic kidney …

Vascular calcification is an actively regulated process resembling bone formation and
contributes to the cardiovascular morbidity and mortality of chronic kidney disease (CKD) …