The emerging roles of irisin in vascular calcification

S Wang, S Hu, Y Pan - Frontiers in Endocrinology, 2024 - frontiersin.org
Vascular calcification is a common accompanying pathological change in many chronic
diseases, which is caused by calcium deposition in the blood vessel wall and leads to …

Vascular Calcification in Rodent Models—Keeping Track with an Extented Method Assortment

J Herrmann, MR Gummi, M Xia, M van der Giet, M Tölle… - Biology, 2021 - mdpi.com
Simple Summary Arterial vessel diseases are the leading cause of death in the elderly and
their accelerated pathogenesis is responsible for premature death in patients with chronic …

[HTML][HTML] The association of renal impairment with different patterns of intracranial arterial calcification: intimal and medial calcification

X Li, H Du, W Yang, J Chen, X Li, X Chen - Atherosclerosis, 2022 - Elsevier
Background and aims Increasing knowledge about calcification together with improved
imaging techniques provided evidence that intracranial arterial calcification (IAC) can be …

Uremic toxins and vascular calcification–missing the forest for all the trees

N Rapp, P Evenepoel, P Stenvinkel, L Schurgers - Toxins, 2020 - mdpi.com
The cardiorenal syndrome relates to the detrimental interplay between the vascular system
and the kidney. The uremic milieu induced by reduced kidney function alters the phenotype …

Mitochondria homeostasis and vascular medial calcification

M Li, Y Zhu, SK Jaiswal, NF Liu - Calcified Tissue International, 2021 - Springer
Vascular calcification occurs highly prevalent, which commonly predicts adverse
cardiovascular events. The pathogenesis of calcification, a complicated and multifactorial …

POSTN promotes diabetic vascular calcification by interfering with autophagic flux

XJ Sun, WQ Ma, Y Zhu, NF Liu - Cellular signalling, 2021 - Elsevier
Autophagy is a lysosomal degradative process that is closely related to the pathogenesis of
vascular calcification. Recent evidence suggests that periostin (POSTN) is a unique …

Fibroblast growth factor 21 inhibits vascular calcification by ameliorating oxidative stress of vascular smooth muscle cells

Y Li, S He, C Wang, W Jian, X Shen, Y Shi… - … and Biophysical Research …, 2023 - Elsevier
Vascular calcification is very common in clinical. Severe vascular calcification is related to
the occurrence of adverse events. Oxidative stress (OS) plays a pathophysiological role in …

Phenylacetylglutamine and trimethylamine N‐oxide: Two uremic players, different actions

S Hobson, AR Qureshi, J Ripswedan… - European Journal of …, 2023 - Wiley Online Library
Background Chronic kidney disease (CKD) patients exhibit a heightened cardiovascular
(CV) risk which may be partially explained by increased medial vascular calcification …

The impacts of dietary antioxidants on cardiovascular events in hemodialysis patients: An update on the cellular and molecular mechanisms

S Zununi Vahed, SM Hejazian, M Ardalan… - Nutrition …, 2024 - academic.oup.com
Cardiovascular-related complications (CVCs) are the primary cause of death in patients
undergoing hemodialysis (HD), accounting for greater than half of all deaths. Beyond …

Sulforaphane upregulates the mRNA expression of NRF2 and NQO1 in non-dialysis patients with chronic kidney disease

M Ribeiro, L Alvarenga, KS Coutinho-Wolino… - Free Radical Biology …, 2024 - Elsevier
Sulforaphane (SFN), found in cruciferous vegetables, is a known activator of NRF2 (master
regulator of cellular antioxidant responses). Patients with chronic kidney disease (CKD) …