Exploring shared mechanisms between ulcerative colitis and psoriasis and predicting therapeutic natural compounds through bioinformatics and molecular docking

Y Yang, Z Gong, J Yang, Y Cai, S Hong, W Mao, Z Guo… - Heliyon, 2024 - cell.com
Introduction Previous studies have suggested a potential correlation between psoriasis (PS)
and ulcerative colitis (UC). However, studies exploring the shared mechanisms of both …

Intestinal mucosa-derived DNA methylation signatures in the penetrating intestinal mucosal lesions of Crohn's disease

Y Li, Z Wang, X Wu, G Wang, G Gu, H Ren, Z Hong… - Scientific Reports, 2021 - nature.com
The purpose of this study was to evaluate genome-wide DNA methylation changes in
intestinal mucosa tissue of adult patients with Crohn's disease comprehensively. DNA …

Possible role of microRNA miRNA-IL-25 interaction in mice with ulcerative colitis

J Yao, R Gao, M Luo, C Wei, B Wu, L Guo, L Wang… - …, 2020 - Taylor & Francis
Background: The regulatory network of ulcerative colitis (UC)-associated miRNAs is not fully
understood. In this study, we aim to investigate the global profile and regulatory network of …

Bioinformatics analysis of immune cell infiltration and diagnostic biomarkers between ankylosing spondylitis and inflammatory bowel disease

X Zhang, T Chen, X Qian, X He - … and Mathematical Methods in …, 2023 - Wiley Online Library
Background. Ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) are both
autoimmune diseases, and they often occur together in clinical practice, but the …

MAD2L1 functions as a novel diagnostic and predictive biomarker in cholangiocarcinoma

Y Gao, Y Liu, L Sun, X Ouyang, C Zhu… - Genetic Testing and …, 2021 - liebertpub.com
Background: Most cholangiocarcinoma (CCA) patients are diagnosed at an advanced stage
of disease, and the postoperational recurrence rates are high in those undergoing resection …

Transcriptome analysis and the prognostic role of NUDC in diffuse and intestinal gastric cancer

SH Jeong, M Park, SY Park, J Park… - … in Cancer Research …, 2021 - journals.sagepub.com
Introduction: There have been few studies about gene differences between patients with
diffuse-type gastric cancer and those with intestinal-type gastric cancer. The aim of this study …

ENHANCING PATIENT STRATIFICATION AND INTERPRETABILITY THROUGH CLASS-CONTRASTIVE AND FEATURE ATTRIBUTION TECHNIQUES

S Olowu, N Lawrence, S Banerjee - medRxiv, 2024 - medrxiv.org
A crucial component of the treatment of genetic disorders is identifying and characterising
the genes and gene modules that drive disease processes. Recent advances in Next …

[HTML][HTML] Identification of hub genes and key modules in laryngeal squamous cell carcinoma

H Li, S Bo, Y Guo, T Wang, Y Pan - Translational Cancer Research, 2024 - ncbi.nlm.nih.gov
Background Laryngeal squamous cell carcinoma (LSCC) is the prominent cancer in head
and neck, which greatly affects life quality of patients. The pathogenesis of LSCC is not …

Differential Gene Expression Profiles Involved in the Inflammations Due to COVID-19 and Inflammatory Bowel Diseases and the Investigation of Predictive Biomarkers

S Aishwarya, K Gunasekaran - Biochemical Genetics, 2024 - Springer
Gastrointestinal manifestations in COVID-19 were attributed to 74–86% of the hospitalised
patients due to severe or prolonged pathogenesis. Though it is a respiratory disease, the …

[HTML][HTML] Identification of breast cancer risk modules via an integrated strategy

W Li, G Deng, J Zhang, E Hu, Y He, J Lv, X Sun… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Breast cancer is one of the most common malignant cancers among females worldwide.
This complex disease is not caused by a single gene, but resulted from multi-gene …