The premetazoan ancestry of the synaptic toolkit and appearance of first neurons

J Colgren, P Burkhardt - Essays in Biochemistry, 2022 - portlandpress.com
Neurons, especially when coupled with muscles, allow animals to interact with and navigate
through their environment in ways unique to life on earth. Found in all major animal lineages …

[HTML][HTML] Ctenophores and the evolutionary origin (s) of neurons

P Burkhardt - Trends in Neurosciences, 2022 - cell.com
Ctenophores (commonly known as comb jellies) are among the earliest branching extant
lineages of the animal kingdom. Here, I present a brief overview of the ctenophore nervous …

[HTML][HTML] Alternative neural systems: what is a neuron?(ctenophores, sponges and placozoans)

LL Moroz, DY Romanova - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
How to make a neuron, a synapse, and a neural circuit? Is there only one 'design'for a
neural architecture with a universally shared genomic blueprint across species? The brief …

[HTML][HTML] Stepwise emergence of the neuronal gene expression program in early animal evolution

SR Najle, X Grau-Bové, A Elek, C Navarrete… - Cell, 2023 - cell.com
The assembly of the neuronal and other major cell type programs occurred early in animal
evolution. We can reconstruct this process by studying non-bilaterians like placozoans …

Adaptive Cellular Radiations and the Genetic Mechanisms Underlying Animal Nervous System Diversification

J Hehmeyer, F Plessier, H Marlow - Annual Review of Cell and …, 2024 - annualreviews.org
In animals, the nervous system evolved as the primary interface between multicellular
organisms and the environment. As organisms became larger and more complex, the …

[HTML][HTML] Recording cilia activity in ctenophores: effects of nitric oxide and low molecular weight transmitters

TP Norekian, LL Moroz - Frontiers in Neuroscience, 2023 - frontiersin.org
Cilia are the major effectors in Ctenophores, but very little is known about their transmitter
control and integration. Here, we present a simple protocol to monitor and quantify cilia …

[HTML][HTML] Kobayashi Award 2021: Neuropeptides, receptors, and follicle development in the ascidian, Ciona intestinalis Type A: New clues to the evolution of chordate …

H Satake - General and Comparative Endocrinology, 2023 - Elsevier
Abstract Ciona intestinalis Type A (Ciona robusta) is a cosmopolitan species belonging to
the phylum Urochordata, invertebrate chordates that are phylogenetically the most closely …

Brief history of Ctenophora

LL Moroz - Ctenophores: Methods and Protocols, 2024 - Springer
Ctenophores are the descendants of the earliest surviving lineage of ancestral metazoans,
predating the branch leading to sponges (Ctenophore-first phylogeny). Emerging genomic …

On the origin of appetite: GLWamide in jellyfish represents an ancestral satiety neuropeptide

V Thoma, S Sakai, K Nagata, Y Ishii… - Proceedings of the …, 2023 - National Acad Sciences
Food intake is regulated by internal state. This function is mediated by hormones and
neuropeptides, which are best characterized in popular model species. However, the …

[HTML][HTML] Large-scale deorphanization of Nematostella vectensis neuropeptide G protein-coupled receptors supports the independent expansion of bilaterian and …

D Thiel, LAY Guerra, A Kieswetter, AG Cole… - Elife, 2024 - elifesciences.org
Neuropeptides are ancient signaling molecules in animals but only few peptide receptors
are known outside bilaterians. Cnidarians possess a large number of G protein-coupled …