According to the free radical theory, aging can be considered as a progressive, inevitable
process partially related to the accumulation of oxidative damage into biomolecules–nucleic …

Aging is characterized by a progressive decline in the efficiency of physiological function
and by the increased susceptibility to disease and death. The premise of the mitochondrial …

Background: Magnetic bead purification for the analysis of low-abundance proteins in body
fluids facilitates the identification of potential new biomarkers by matrix-assisted laser …

Blood is divided in two compartments, namely, plasma and cells. The latter contain red
blood cells, leukocytes, and platelets. From a descriptive medical discipline, hematology has …

Background: Peptidome profiling of human urine is a promising tool to identify novel disease-
associated biomarkers; however, a wide range of preanalytical variables influence the …

In this review, we lead the reader through the evolution of proteomics application to the
study of quality control in production processes of foods (including food of plant origin and …

Substantial advances have been made in the fundamental understanding of human biology,
ranging from DNA structure to identification of diseases associated with genetic …

Early diagnosis is important for effective disease management. Measurement of biomarkers
present at the local level of the skin could be advantageous in facilitating the diagnostic …

Methods A transient 20-min forebrain ischemia followed by 1, 6 or 24 h of reperfusion was
induced in Sprague-Dawley rats by bilateral common carotid artery occlusion and …

PURPOSE: Prostate Cancer (PCa) represents the second most frequent type of tumor in
men worldwide. Incidence increases with patient age and represents the most important risk …