[HTML][HTML] Systematic review: targeted molecular imaging of angiogenesis and its mediators in rheumatoid arthritis

F Khodadust, A Ezdoglian, MM Steinz… - International journal of …, 2022 - mdpi.com
Extensive angiogenesis is a characteristic feature in the synovial tissue of rheumatoid
arthritis (RA) from a very early stage of the disease onward and constitutes a crucial event …

[HTML][HTML] Role of the Hippo pathway in autoimmune diseases

H Kong, JJ Han, D Gorbachev, XA Zhang - Experimental Gerontology, 2024 - Elsevier
The immune system is an important defense against diseases, and it is essential to maintain
the homeostasis of the body's internal environment. Under normal physiological conditions …

Targeting the IL-6–Yap–Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis

RA Symons, F Colella, FL Collins, AJ Rafipay… - Annals of the …, 2022 - ard.bmj.com
Objective We aimed to understand the role of the transcriptional co-factor Yes-associated
protein (Yap) in the molecular pathway underpinning the pathogenic transformation of …

Actin cytoskeleton in angiogenesis

N Yadunandanan Nair, V Samuel, L Ramesh… - Biology …, 2022 - journals.biologists.com
Actin, one of the most abundant intracellular proteins in mammalian cells, is a critical
regulator of cell shape and polarity, migration, cell division, and transcriptional response …

[HTML][HTML] Carboxyamidotriazole alleviates pannus formation and cartilage erosion in rats with adjuvant arthritis

Y Zhou, X Yang, J Liu, M Yang, C Ye, L Zhu - Heliyon, 2023 - cell.com
Carboxyamidotriazole (CAI) was initially considered a non-cytotoxic anticancer agent.
However, recently, pronounced anti-inflammatory properties of CAI have been reported …

[HTML][HTML] Coix seed oil alleviates synovial angiogenesis through suppressing HIF-1α/VEGF-A signaling pathways via SIRT1 in collagen-induced arthritis rats

Q Xu, H Kong, S Ren, F Meng, R Liu, H Jin, J Zhang - Chinese Medicine, 2023 - Springer
Background Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by
symmetric arthritis. Coix Seed Oil (CSO) has been shown to reduce inflammation in collagen …

[HTML][HTML] Proteome analysis reveals novel serum biomarkers for Henoch-Schönlein purpura in Chinese children

L Liu, H Liu, K Zhu, L Zhang, X Yin, L Han, M Wang… - Journal of …, 2023 - Elsevier
Abstract Purpose Henoch-Schönlein purpura (HSP) is diagnosed based on characteristic
skin changes. This study aimed to identify the serum biomarkers of HSP in children …

Yap expression is closely related to tumor angiogenesis and poor prognosis in hepatoblastoma

W Gong, Z Han, F Fang, L Chen - Fetal and Pediatric Pathology, 2022 - Taylor & Francis
Background: Hepatoblastoma (HB) is malignant embryonal tumor typically arising in infants
and young children. Yes-associated protein (YAP) is aberrantly activated in various tumors; …

The Hippo-YAP Signaling Pathway in Osteoarthritis and Rheumatoid Arthritis

M Li, FJ Zhang, RJ Bai - Journal of Inflammation Research, 2024 - Taylor & Francis
Arthritis is the most prevalent joint disease and is characterized by articular cartilage
degradation, synovial inflammation, and changes in periarticular and subchondral bone …

[HTML][HTML] Exosomes and exosomal miRNAs: A new avenue for the future treatment of rheumatoid arthritis

Y Liu, P Jiang, Y Qu, C Liu, D Zhang, B Xu, Q Zhang - Heliyon, 2024 - cell.com
Rheumatoid arthritis is a chronic systemic autoimmune disease that involves mainly
synovitis and joint injury and is one of the main causes of disability. The pathogenesis of …