The complement cascade is an important arm of the immune system that plays a key role in
protecting the central nervous system (CNS) from infection. Recently, it has also become …

The complement system is an essential part of innate immunity, typically conferring
protection via eliminating pathogens and accumulating debris. However, the defensive …

Neurological disorders are major contributors to death and disability worldwide. The
pathology of injuries and disease processes includes a cascade of events that often involve …

Stroke is a devastating medical condition, killing millions of people each year and causing
serious injury to many more. Despite advances in treatment, there is still little that can be …

Stroke is the third leading cause of death in industrialized countries and one of the largest
causes of permanent disability worldwide. Therapeutic options to fight stroke are still limited …

Background and Purpose: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection is associated with an increased rate of cerebrovascular events including ischemic …

Axon regenerative failure in the mature CNS contributes to functional deficits following many
traumatic injuries, ischemic injuries, and neurodegenerative diseases. The complement …

Altered energy metabolism of cancer cells shapes the immune cell response in the tumor
microenvironment that facilitates tumor progression. Herein, we reported the novel of tumor …

The complement system is an assembly of proteins that collectively participate in the
functions of the healthy and diseased brain. The complement system plays an important role …

Significance: Endothelial cells lining the lumen of blood vessels play an important role in the
regulation of cardiovascular functions through releasing both vasoconstricting and …