Establishment of Membrane-Bound IgA1-Specific Antibody Possessing Antibody-Dependent Cellular Cytotoxicity Activity

K Yamasaki, E Kaneko, K Mori - Monoclonal Antibodies in …, 2022 - liebertpub.com
Therapeutic agents targeting B cells, such as rituximab, have been proven to be effective in
several diseases. However, since this therapy targets the whole B cell population, there are …

[PDF][PDF] Engineered Antibodies with Dual Inhibitory Activity against Toll-like Receptor Family Members

佐藤雅人, サトウマサヒト - 2023 - tsukuba.repo.nii.ac.jp
The immune system plays a crucial role in host defense in vertebrates. One of the major
players in the immune system is the antibody, which recognizes antigens to eliminate …

Manipulating mIgD-expressing B cells with anti-migis-δ monoclonal antibodies

NY Chen, AFH Hung, CJ Lin, JB Chen, HM Chu… - Molecular …, 2013 - Elsevier
Surface IgD and IgM doubly positive cells comprise the major population of B cells in the
human immune system. The heavy chain of membrane-bound IgD (mδ) differs from that of …